Search
Glutamate receptor ionotropic, NMDA 1
go.drugbank.com/bio_entities/BE0000365TargetHumansComponent of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:21376300, PubMed:26875626, PubMed:26...
Polypeptides: Glutamate receptor ionotropic, NMDA 1Synonyms: Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1Glutamate receptor ionotropic, NMDA 2D
go.drugbank.com/bio_entities/BE0000396TargetHumansComponent of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:26875626, PubMed:27616483, PubMed:28...
Polypeptides: Glutamate receptor ionotropic, NMDA 2DSynonyms: N-methyl D-aspartate receptor subtype 2D, Glutamate [NMDA] receptor subunit epsilon-4Glycine receptor subunit alpha-3
go.drugbank.com/bio_entities/BE0000414TargetHumansGlycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:26416729, PubMed:9677400). Channel characteristics depend on the subunit composition; heteropentameric channels display f...
Polypeptides: Glycine receptor subunit alpha-3Activin receptor type-1-like
go.drugbank.com/bio_entities/BE0000459TargetHumansType I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. … On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
Polypeptides: Activin receptor type-1-likeSynonyms: Activin receptor-like kinase 1, TGF-B superfamily receptor type IInterleukin-1 receptor type 1
go.drugbank.com/bio_entities/BE0000565TargetHumansReceptor for IL1A, IL1B and IL1RN (PubMed:2950091, PubMed:37315560). … Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits.
Polypeptides: Interleukin-1 receptor type 1Synonyms: Interleukin-1 receptor alpha, Interleukin-1 receptor type IGrowth hormone-releasing hormone receptor
go.drugbank.com/bio_entities/BE0000625TargetHumansReceptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion
Polypeptides: Growth hormone-releasing hormone receptorSynonyms: GRF receptor, GHRH receptorGlutamate receptor ionotropic, NMDA 3A
go.drugbank.com/bio_entities/BE0000641TargetHumansForms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits (PubMed:38598639). … Forms glutamatergic receptor complexes with GluN1 and GluN2 subunits which are activated by glycine binding to the GluN1 and GluN3 subunits and L-glutamate binding to GluN2 subunits (By similarity).
Polypeptides: Glutamate receptor ionotropic, NMDA 3ASynonyms: N-methyl-D-aspartate receptor subtype 3AInterleukin-2 receptor subunit beta
go.drugbank.com/bio_entities/BE0000651TargetHumansReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Polypeptides: Interleukin-2 receptor subunit betaSynonyms: IL-2 receptor subunit beta, High affinity IL-2 receptor subunit betaUrokinase plasminogen activator surface receptor
go.drugbank.com/bio_entities/BE0000717TargetHumansGPI-anchored receptor that recruits and activates the urokinase-type plasminogen activator (uPA) at the cell surface.
Polypeptides: Urokinase plasminogen activator surface receptorGranulocyte colony-stimulating factor receptor
go.drugbank.com/bio_entities/BE0000793TargetHumansReceptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation.
Polypeptides: Granulocyte colony-stimulating factor receptorSynonyms: G-CSF receptor