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AN0128
go.drugbank.com/drugs/DB05054InvestigationalAN0128 is a good candidate for a topical antibiotic and is currently being developed by Anacor as a novel therapeutic for acne and atopic dermatitis. … Of particular importance is P. acnes and its causal role in acne vulgaris. The rise in antibiotic resistance of P. acnes to standard antibiotics necessitates the development of new treatment agents.
Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15740InvestigationalHuman olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) reside in an accessible location of the nasal cavity and have properties of multipotency and high proliferation, which contributes to high … In humans, OM-MSCs are derived from the olfactory mucosa which is collected in vivo through rhinoscopy techniques and nasal forceps.
ORE-1001
go.drugbank.com/drugs/DB12271InvestigationalORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor.
Categories: Amino Acids, Peptides, and ProteinsProtionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Categories: rifabutin, pyrazinamide and protionamide, pyrazinamide, ethambutol, protionamide and lomefloxacinCardiac Arrest
go.drugbank.com/conditions/DBCOND0031003Synonyms: Cardiac Arrest (CA), CA - Cardiac arrestDomofenogene zalfaparvovec
go.drugbank.com/drugs/DB16810InvestigationalDomofenogene zalfaparvovec, formerly known as BMN-307, is an investigational AAV5-phenylalanine hydroxylase (PAH) gene therapy developed by BioMarin Pharmaceutical.
Cocarboxylase
go.drugbank.com/drugs/DB01987ApprovedInvestigationalThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Categories: Enzymes and CoenzymesICA-105665
go.drugbank.com/drugs/DB06089InvestigationalIt is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy. … In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain.
Advanced Prostate Cancer
go.drugbank.com/conditions/DBCOND0043429Synonyms: Ca prostate, CA - Cancer of prostateVelusetrag
go.drugbank.com/drugs/DB12702InvestigationalVelusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance.