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Displaying results 6491 - 6500 of 10000 in total
  1. Drug

    Rolicyclidine

    go.drugbank.com/drugs/DB01549
    ExperimentalIllicit

    Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. … Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.

  2. Drug

    Amredobresib

    go.drugbank.com/drugs/DB21566
    Investigational

    Amredobresib is under investigation in clinical trial NCT02516553 (BI 894999 First in Human Dose Finding Study in Advanced Malignancies). Amredobresib has a monoisotopic molecular weight of 467.25 Da. … The usage of the INN stem '-bresib' in the name indicates that Amredobresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic.

  3. Drug

    Tegtociclib

    go.drugbank.com/drugs/DB21635
    Investigational

    Tegtociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Tegtociclib is a cyclin dependant kinase inhibitor. … Tegtociclib is under investigation in clinical trial NCT05262400 (A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid

  4. Drug

    ETC-588

    go.drugbank.com/drugs/DB05456
    Experimental

    Esperion is currently developing ETC-588 as a treatment for patients with acute coronary syndromes. … and other lipids from cells including those in the arterial wall.

  5. Drug

    NRP369

    go.drugbank.com/drugs/DB06384
    Experimental

    NRP369 is an oxycodone derivative under investigation for the treatment of pain (moderate to moderately severe). NRP369 was developed by New River Pharmaceuticals as a backup therapeutic to [NRP290].

  6. Drug

    Telenzepine

    go.drugbank.com/drugs/DB19508
    Investigational

    Telenzepine is a small molecule drug. The usage of the INN stem '-zepine' in the name indicates that Telenzepine is a tricyclic compound. … Telenzepine is under investigation in clinical trial NCT01155531 (Safety & Tolerability of a Combination of Antidepressant and Peptic Ulcer Drug in Overweight Healthy Subjects).

  7. Drug

    Setileuton

    go.drugbank.com/drugs/DB19550
    Investigational

    Setileuton is under investigation in clinical trial NCT00404313 (The Effect of MK0633 in Patients With Chronic Asthma (0633-007)). Setileuton has a monoisotopic molecular weight of 463.12 Da. … Setileuton is a small molecule drug. The usage of the INN stem '-leuton' in the name indicates that Setileuton is a 5-lipo-oxygenase inhibitor, anti-inflammatory.

  8. Drug

    Felezonexor

    go.drugbank.com/drugs/DB21067
    Investigational

    Felezonexor is under investigation in clinical trial NCT02667873 (A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors). … Felezonexor is a small molecule drug. The usage of the INN stem '-nexor' in the name indicates that Felezonexor is a nuclear export inhibitor.

  9. Drug

    Icovamenib

    go.drugbank.com/drugs/DB21669
    Investigational

    Icovamenib is under investigation in clinical trial NCT06152042 (Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus). Icovamenib has a monoisotopic molecular weight of 566.28 Da. … Icovamenib is a small molecule drug. The usage of the INN stem '-menib' in the name indicates that Icovamenib is a menin interaction inhibitor.

  10. Drug

    Firocoxib

    go.drugbank.com/drugs/DB09217
    ExperimentalVet approved

    Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. … Firocoxib is not intended or approved for use in human medicine.