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Displaying results 61 - 70 of 198 in total
  1. Pathway

    Nicotine Action Pathway

    smpdb.ca/view/SMP0000431
    Drug action

    This causes the channel to open and allow conductance of multiple cations including sodium, calcium, and potassium. … Dopamine binding to its receptors is responsible the euphoric and addictive properties of nicotine.

    Drugs: NADH · ATP · Nicotine · Norepinephrine · Dopamine · Potassium cation +5 more
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  2. Pathway

    Cocaine Action Pathway

    smpdb.ca/view/SMP0000395
    Drug action

    Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.

    Drugs: ATP · Norepinephrine · Cocaine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  3. Pathway

    Dibucaine Action Pathway

    smpdb.ca/view/SMP0000396
    Drug action

    Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.

    Drugs: ATP · Norepinephrine · Cinchocaine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  4. Pathway

    Levobupivacaine Action Pathway

    smpdb.ca/view/SMP0000397
    Drug action

    Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.

    Drugs: ATP · Norepinephrine · Dopamine · Levobupivacaine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  5. Pathway

    Lidocaine (Local Anaesthetic) Action Pathway

    smpdb.ca/view/SMP0000398
    Drug action

    Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.

    Drugs: NADH · ATP · Lidocaine · Norepinephrine · Dopamine · Potassium cation +3 more
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  6. Pathway

    Oxybuprocaine Action Pathway

    smpdb.ca/view/SMP0000400
    Drug action

    Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.

    Drugs: ATP · Norepinephrine · Oxybuprocaine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  7. Pathway

    Procaine Action Pathway

    smpdb.ca/view/SMP0000402
    Drug action

    Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.

    Drugs: ATP · Norepinephrine · Procaine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  8. Pathway

    Sufentanil Action Pathway

    smpdb.ca/view/SMP0000417
    Drug action

    and decrease in cAMP production. … It also inhibits nociceptive neurotransmitter release and induces membrane hyperpolarization. Analgesia, anesthesia, and respiratory depression are a consequence of remifentanial’s action.

    Drugs: ATP · Norepinephrine · Sufentanil · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  9. Pathway

    Desipramine Action Pathway

    smpdb.ca/view/SMP0000423
    Drug action

    This increases the concentrations of both norepinephrine and serotonin in their respective synapses and reverses the state of low concentrations of both neurotransmitters found in depression. … CREB-1 enters the nucleus and affects transcription of brain-derived neurotrophic factor (BDNF).

    Drugs: ATP · Norepinephrine · Dopamine · Desipramine · Potassium cation · Calcium +1 more
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  10. Pathway

    Escitalopram Action Pathway

    smpdb.ca/view/SMP0000425
    Drug action

    CREB-1 enters the nucleus and affects transcription of brain-derived neurotrophic factor (BDNF). … This increases the concentrations of serotonin in the synaptic cleft and reverses the state of low concentration seen in depression.

    Drugs: ATP · Norepinephrine · Dopamine · Escitalopram · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1