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Serine/threonine-protein kinase/endoribonuclease IRE1
go.drugbank.com/bio_entities/BE0003839TargetHumansIn unstressed cells, the endoplasmic reticulum luminal domain is maintained in its inactive monomeric state by binding to the endoplasmic reticulum chaperone HSPA5/BiP (PubMed:21317875). … Accumulation of misfolded proteins in the endoplasmic reticulum causes release of HSPA5/BiP, allowing the luminal domain to homodimerize, promoting autophosphorylation of the kinase domain and subsequent
Synonyms: Endoplasmic reticulum-to-nucleus signaling 1Aspiration Pneumonia
go.drugbank.com/conditions/DBCOND0031880Drugs: PrednisoloneSynonyms: Pneumonitis due to inhalation of food and vomitInfluenza Type B
go.drugbank.com/conditions/DBCOND0041710Drugs: OseltamivirSynonyms: Influenza due to other identified influenza virusUrticaria Cold
go.drugbank.com/conditions/DBCOND0162077Drugs: CyproheptadineSynonyms: Urticaria due to cold (disorder)Nitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigational[L42445] It is also used to induce intraoperative hypotension.[L7099] … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins.
Products: TOP-NITRO, NITROGLICERINA PH&TDiabetic Ketoacidosis
go.drugbank.com/conditions/DBCOND0000979Synonyms: Ketoacidosis due to diabetes mellitus, Ketoacidosis due to diabetes mellitus (disorder)Blood Transfusion Complications
go.drugbank.com/conditions/DBCOND0086922Synonyms: Circulatory overload due to transfusion, Dyspnea due to and following transfusionFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigational[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Products: FENO-TG 160mg tabletConjunctivitis
go.drugbank.com/conditions/DBCOND0009989Drugs: Betamethasone · Chlorpheniramine · Dexamethasone · Dexchlorpheniramine · Framycetin · Gramicidin D +11 moreSynonyms: Infection due to Moraxella bovis, Keratoconjunctivitis due to Moraxella bovisHaemophilus Influenzae Infections
go.drugbank.com/conditions/DBCOND0042753Drugs: Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigenSynonyms: [X]Haemophilus influenzae [h influenzae] as the cause of diseases classified to other chapters, [X]Hemophilus influenzae [h influenzae] as the cause of diseases classified to other chapters