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Toll-like receptor 5
go.drugbank.com/bio_entities/BE0011820TargetHumansPattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781).
Polypeptides: Toll-like receptor 5Synonyms: Toll/interleukin-1 receptor-like protein 3Complement receptor type 1
go.drugbank.com/bio_entities/BE0012722TargetHumansMembrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069).
Polypeptides: Complement receptor type 1Synonyms: C3b/C4b receptorNeurotensin receptor type 1
go.drugbank.com/bio_entities/BE0013004TargetHumansG protein-coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:21725197, PubMed:23140271, PubMed:8381365).
Polypeptides: Neurotensin receptor type 1Synonyms: High-affinity levocabastine-insensitive neurotensin receptorBombesin receptor subtype-3
go.drugbank.com/bio_entities/BE0013148TargetHumansThis receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Bombesin receptor subtype-3Function: bombesin receptor activityGalanin receptor type 1
go.drugbank.com/bio_entities/BE0013287TargetHumansReceptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity
Polypeptides: Galanin receptor type 1Function: galanin receptor activityInterleukin-18 receptor 1
go.drugbank.com/bio_entities/BE0014121TargetHumansWithin the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:14528293, PubMed:25261253, PubMed:25500532, PubMed:37993714, PubMed:8626725
Polypeptides: Interleukin-18 receptor 1Synonyms: IL1 receptor-related protein, Interleukin-18 receptor alphaAtypical chemokine receptor 1
go.drugbank.com/bio_entities/BE0015068TargetHumansAlso known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. … Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC.
Polypeptides: Atypical chemokine receptor 1Synonyms: Plasmodium vivax receptor, Duffy antigen/chemokine receptorInterferon lambda receptor 1
go.drugbank.com/bio_entities/BE0016547TargetHumansThe IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. … Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
Polypeptides: Interferon lambda receptor 1Synonyms: IFN-lambda receptor 1, IL-28 receptor subunit alphaInterleukin-17 receptor D
go.drugbank.com/bio_entities/BE0017358TargetHumansFeedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12807873, PubMed:12958313). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK wi...
Polypeptides: Interleukin-17 receptor DSynonyms: IL-17 receptor D, Interleukin-17 receptor-like proteinLysophosphatidic acid receptor 1
go.drugbank.com/bio_entities/BE0017535TargetHumansReceptor for lysophosphatidic acid (LPA) (PubMed:19306925, PubMed:25025571, PubMed:26091040, PubMed:9070858). … Through its function as LPA receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding (PubMed:18066075, PubMed:19656035, PubMed:19733258).
Polypeptides: Lysophosphatidic acid receptor 1Synonyms: LPA receptor 1, Lysophosphatidic acid receptor Edg-2