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Displaying results 721 - 730 of 10000 in total
  1. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]

    Mixtures: WICK MediNait Erkältungssirup für die Nacht, DS Never Cold SCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 Agonist
  2. Target

    Laminin subunit alpha-1

    go.drugbank.com/bio_entities/BE0002108
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a li...

    Synonyms: S-LAM alpha, S-laminin subunit alpha
  3. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … well as athlete's foot [A174097].

    Mixtures: LINDAZOL-2 ®, LINDAZOL-2 ®Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
  4. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

    Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte SInternational brands: Slow-K, Micro-K
  5. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0001684
    TargetHumans

    Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity)

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  6. Target

    Cytosol aminopeptidase

    go.drugbank.com/bio_entities/BE0003882
    TargetHumans

    For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. … Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status

    Synonyms: Peptidase S, Cysteinylglycine-S-conjugate dipeptidase
  7. Indication

    Adrenal Cushing Syndrome

    go.drugbank.com/conditions/DBCOND0148294
    Drugs: Mitotane
    Synonyms: Cushing s Syndrome
  8. Target

    Complement C1s subcomponent

    go.drugbank.com/bio_entities/BE0001529
    TargetEnzymeHumans

    Component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the ...

    Synonyms: Complement component 1 subcomponent s
  9. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0000542
    TargetHumans

    Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)

    Synonyms: Peptidyl-cysteine S-nitrosylase GAPDH
  10. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol is on the World Health Organization's List of Essential Medicines. … It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics.

    Mixtures: Cortane-B, Cortaine -B AqueousCategories: Compounds used in a research, industrial, or household setting