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Displaying results 721 - 730 of 1186 in total
  1. Target

    Neuronal acetylcholine receptor subunit alpha-3

    go.drugbank.com/bio_entities/BE0003585
    TargetHumans

    CHRNA3:CHRNB4 being predominant in neurons of the autonomic ganglia, it is known as ganglionic nicotinic receptor (PubMed:31488329).

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-3
  2. Target

    Gamma-aminobutyric acid receptor subunit theta

    go.drugbank.com/bio_entities/BE0003597
    TargetHumans

    Theta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:16412217). GABA-gated chloride channels, also named GA...

    Polypeptides: Gamma-aminobutyric acid receptor subunit thetaSynonyms: GABA(A) receptor subunit theta
  3. Target

    Gamma-aminobutyric acid receptor subunit delta

    go.drugbank.com/bio_entities/BE0003599
    TargetHumans

    Delta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:35355020). GABA-gated chloride channels, also named GABA(A) receptors (...

    Polypeptides: Gamma-aminobutyric acid receptor subunit deltaSynonyms: GABA(A) receptor subunit delta
  4. Target

    BDNF/NT-3 growth factors receptor

    go.drugbank.com/bio_entities/BE0003605
    TargetHumans

    Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. … Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2 (PubMed:15494731, PubMed:7574684).

    Polypeptides: BDNF/NT-3 growth factors receptorSynonyms: Neurotrophic tyrosine kinase receptor type 2
  5. Target

    Receptor-type tyrosine-protein phosphatase beta

    go.drugbank.com/bio_entities/BE0003769
    TargetHumans

    Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadhe...

    Polypeptides: Receptor-type tyrosine-protein phosphatase beta
  6. Target

    T cell receptor beta constant 1

    go.drugbank.com/bio_entities/BE0003779
    TargetHumans

    Constant region of T cell receptor (TR) beta chain (PubMed:24600447).

    Polypeptides: T cell receptor beta constant 1
  7. Target

    Cation-dependent mannose-6-phosphate receptor

    go.drugbank.com/bio_entities/BE0004494
    TargetTransporterHumans

    Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal

    Polypeptides: Cation-dependent mannose-6-phosphate receptorSynonyms: CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptor
  8. Target

    Receptor tyrosine-protein kinase erbB-4

    go.drugbank.com/bio_entities/BE0004772
    TargetHumans

    Acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. … Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors.

    Polypeptides: Receptor tyrosine-protein kinase erbB-4Synonyms: Tyrosine kinase-type cell surface receptor HER4
  9. Target

    Membrane-associated progesterone receptor component 1

    go.drugbank.com/bio_entities/BE0004896
    TargetHumans

    Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization (PubMed:30443021)

    Polypeptides: Membrane-associated progesterone receptor component 1
  10. Target

    GABA(A) Receptor Benzodiazepine Binding Site

    go.drugbank.com/bio_entities/BE0008668
    TargetHumans

    GABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response (By similarity). … GABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response in a gamma-2 subunit-controlled manner (By similarity)

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2