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Maleylacetoacetate isomerase
go.drugbank.com/bio_entities/BE0000819TargetEnzymeHumansBifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Also has low glutathione peroxidase activity with T-butyl and...
Synonyms: Glutathione S-transferase zeta 1Adenosylhomocysteinase
go.drugbank.com/bio_entities/BE0003776TargetMycobacterium tuberculosisMay play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
Synonyms: S-adenosyl-L-homocysteine hydrolaseAdenosine deaminase
go.drugbank.com/bio_entities/BE0009226TargetPlasmodium falciparum (isolate 3D7)Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741, PubMed:31002765). Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine bio...
Synonyms: S-methyl-5'-thioadenosine deaminaseDimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigational[L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinateLevodropropizine
go.drugbank.com/drugs/DB12472InvestigationalLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 MLProducts: DROPOLEV-S 30 MG/5 ML ŞURUP, İSODOS 60 MG/5 ML ŞURUP, 1 ADETCytochrome P450 2C9
go.drugbank.com/bio_entities/BE0002793TargetEnzymeHumansOxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol (PubMed:11950794). … Contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan (PubMed:25994031)
Synonyms: (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenaseAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigational[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. … Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis.
Mixtures: HERPAZON % 5 + % 1 KREM, 5 GRAM, Activir Duo 50 mg/g + 10 mg/g CremeCategories: MATE 1 Substrates, MATE 2 SubstratesMethionine synthase
go.drugbank.com/bio_entities/BE0003310TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
Synonyms: 5-methyltetrahydrofolate S-homocysteine methyltransferaseProtein S100-A2
go.drugbank.com/bio_entities/BE0003602TargetHumansMay function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May a...
Synonyms: Protein S-100LArsenite methyltransferase
go.drugbank.com/bio_entities/BE0005015TargetEnzymeHumansCatalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is redu...
Synonyms: S-adenosyl-L-methionine:arsenic(III) methyltransferase