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Displaying results 741 - 750 of 2674 in total
  1. Target

    N-formyl peptide receptor 1

    go.drugbank.com/bio_entities/BE0000995
    TargetHumans

    Differential signaling is also defined by receptor oligomerization state. … Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis (PubMed:15210802).

    Polypeptides: N-formyl peptide receptor 1Synonyms: fMLP receptor, fMet-Leu-Phe receptor
  2. Target

    Atrial natriuretic peptide receptor 2

    go.drugbank.com/bio_entities/BE0000997
    TargetHumans

    Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth

    Polypeptides: Atrial natriuretic peptide receptor 2Synonyms: Atrial natriuretic peptide receptor type B
  3. Target

    Peroxisome proliferator-activated receptor delta

    go.drugbank.com/bio_entities/BE0001007
    TargetHumans

    Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. … Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid.

    Polypeptides: Peroxisome proliferator-activated receptor deltaSynonyms: Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2
  4. Target

    Trace amine-associated receptor 1

    go.drugbank.com/bio_entities/BE0001044
    TargetHumans

    Also functions as a receptor for various drugs and psychoactive substances, such as amphetamine and methamphetamine (PubMed:31399635, PubMed:37935376, PubMed:37935377). … Intracellular G protein-coupled receptor for trace amines, which recognizes endogenous amine-containing metabolites such as beta-phenylethylamine (beta-PEA), 3-iodothyronamine (T1AM), isoamylamine (IAA

    Polypeptides: Trace amine-associated receptor 1Synonyms: Trace amine receptor 1
  5. Target

    Cytokine receptor common subunit gamma

    go.drugbank.com/bio_entities/BE0002102
    TargetHumans

    Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770)

    Polypeptides: Cytokine receptor common subunit gammaSynonyms: IL-2 receptor subunit gamma, Interleukin-2 receptor subunit gamma
  6. Target

    Cytokine receptor common subunit beta

    go.drugbank.com/bio_entities/BE0002115
    TargetHumans

    Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA (PubMed:1495999). … Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells.

    Polypeptides: Cytokine receptor common subunit betaSynonyms: GM-CSF/IL-3/IL-5 receptor common beta subunit
  7. Target

    Fibroblast growth factor receptor 1

    go.drugbank.com/bio_entities/BE0002131
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and

    Polypeptides: Fibroblast growth factor receptor 1Synonyms: Basic fibroblast growth factor receptor 1
  8. Target

    Fibroblast growth factor receptor 3

    go.drugbank.com/bio_entities/BE0002133
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.

    Polypeptides: Fibroblast growth factor receptor 3
  9. Target

    Prostaglandin E2 receptor EP3 subtype

    go.drugbank.com/bio_entities/BE0002375
    TargetHumans

    Receptor for prostaglandin E2 (PGE2) (PubMed:7883006, PubMed:7981210, PubMed:8117308, PubMed:8135729, PubMed:8307176). … The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium (PubMed:7883006, PubMed:7981210, PubMed:8117308

    Polypeptides: Prostaglandin E2 receptor EP3 subtypeSynonyms: PGE receptor EP3 subtype, Prostanoid EP3 receptor
  10. Target

    Interleukin-4 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0002420
    TargetHumans

    In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 … Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation.

    Polypeptides: Interleukin-4 receptor subunit alphaSynonyms: IL-4 receptor subunit alpha