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Displaying results 751 - 760 of 10000 in total
  1. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression.

    Products: CITALOPRAM ABZ 10MG, CITALOPRAM HEXAL 10MG
  2. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    [A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer. … [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma.

    Categories: Antineoplastic and Immunomodulating Agents, Topoisomerase I InhibitorsProducts: TARCKORIN ® 100MG, CAMPTO 100MG/5ML INJECTION
  3. Drug

    Ammonium chloride

    go.drugbank.com/drugs/DB06767
    ApprovedInvestigationalVet approved

    Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.

    Mixtures: Cough and Allergy Syrup With Codeine, I-22 SYRUPCategories: Blood and Blood Forming Organs, Genito Urinary System and Sex Hormones
  4. Drug

    Orphenadrine

    go.drugbank.com/drugs/DB01173
    ApprovedInvestigational

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

    Mixtures: Hovid Paracetamol and Orphenadrine Citrate Tablet 450mg/35mg, Orphenadrine Citrate, Aspirin and CaffeineCategories: Metabolic Side Effects of Drugs and Substances
  5. Drug

    Ginseng

    go.drugbank.com/drugs/DB01404
    ApprovedInvestigationalNutraceutical

    Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties … Ginseng is also known to contain phytoestrogens.

    Mixtures: Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals.Categories: Herbs and Natural Products
  6. Pathway

    The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria

    smpdb.ca/view/SMP0002359
    Disease

    The compound 2-hydroxyglutarate is the product of gain-of-function mutations producing mutIDH1 and mutIDH2 in the cytosolic and mitochondrial isoforms of isocitrate dehydrogenase (IDH). … D-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies.

    Drugs: Pyruvic acid · Biotin · L-Glutamine · Succinic acid · Glutamic acid · NADH +6 more
  7. Drug

    Ferric derisomaltose

    go.drugbank.com/drugs/DB15617
    ApprovedInvestigational

    The latter is an iron carbohydrate oligosaccharide that works to release iron. Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January 2020. … Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide.

    Products: Monofer 100mg/ml solution for injection/infusion in ampoules, Monofer 100 mg/ml solution for injection/infusion in vials
  8. Drug

    Everolimus

    go.drugbank.com/drugs/DB01590
    ApprovedInvestigational

    Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.

    Categories: Antineoplastic and Immunomodulating AgentsProducts: Afinitor Tablet 10mg, Afinitor Tablet 5mg
  9. Drug

    Albutrepenonacog alfa

    go.drugbank.com/drugs/DB13884
    Approved

    [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. … It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305]

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Coagulation factor IX (recombinant), albumin fusion protein, Coagulation Factor IX (Recombinant), Albumin Fusion Protein (rIX-FP)
  10. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … As a result, supplementation with 1-5mg of folic acid is recommended to prevent deficiency and a number of side effects associated with MTX therapy including mouth ulcers and gastrointestinal irritation

    Mixtures: Stress Formula Multi-B Comp + 500mg Vit C Cap, Vitamin B Compound W Vit C 250mg TabCategories: Diet, Food, and Nutrition, Folic Acid and Derivatives