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Proteinase-activated receptor 2
go.drugbank.com/bio_entities/BE0010726TargetHumansMediates inhibition of TNF stimulated JNK phosphorylation via coupling to GNAQ and GNA11; the function involves dissociation of RIPK1 and TRADD from TNFR1. … Receptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455).
Polypeptides: Proteinase-activated receptor 2Synonyms: Thrombin receptor-like 1, G protein-coupled receptor 11Gastric inhibitory polypeptide receptor
go.drugbank.com/bio_entities/BE0011012TargetHumansThis is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase
Polypeptides: Gastric inhibitory polypeptide receptorSynonyms: Glucose-dependent insulinotropic polypeptide receptorToll-like receptor 5
go.drugbank.com/bio_entities/BE0011820TargetHumansPattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781).
Polypeptides: Toll-like receptor 5Synonyms: Toll/interleukin-1 receptor-like protein 3Complement receptor type 1
go.drugbank.com/bio_entities/BE0012722TargetHumansMembrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069).
Polypeptides: Complement receptor type 1Synonyms: C3b/C4b receptorNeurotensin receptor type 1
go.drugbank.com/bio_entities/BE0013004TargetHumansSignaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. … G protein-coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:21725197, PubMed:23140271, PubMed:8381365).
Polypeptides: Neurotensin receptor type 1Synonyms: High-affinity levocabastine-insensitive neurotensin receptorBombesin receptor subtype-3
go.drugbank.com/bio_entities/BE0013148TargetHumansThis receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Bombesin receptor subtype-3Function: bombesin receptor activityGalanin receptor type 1
go.drugbank.com/bio_entities/BE0013287TargetHumansReceptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity
Polypeptides: Galanin receptor type 1Function: galanin receptor activityInterleukin-18 receptor 1
go.drugbank.com/bio_entities/BE0014121TargetHumansWithin the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:14528293, PubMed:25261253, PubMed:25500532, PubMed:37993714, PubMed:8626725
Polypeptides: Interleukin-18 receptor 1Synonyms: IL1 receptor-related protein, Interleukin-18 receptor alphaAtypical chemokine receptor 1
go.drugbank.com/bio_entities/BE0015068TargetHumansAtypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead … Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor.
Polypeptides: Atypical chemokine receptor 1Synonyms: Plasmodium vivax receptor, Duffy antigen/chemokine receptorInterferon lambda receptor 1
go.drugbank.com/bio_entities/BE0016547TargetHumansThe IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. … Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
Polypeptides: Interferon lambda receptor 1Synonyms: IFN-lambda receptor 1, IL-28 receptor subunit alpha