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Somatostatin receptor type 1
go.drugbank.com/bio_entities/BE0000452TargetHumansReceptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Polypeptides: Somatostatin receptor type 15-hydroxytryptamine receptor 1F
go.drugbank.com/bio_entities/BE0000460TargetHumansReceptor for lasmiditan, a drug for the treatment of acute migraine (PubMed:34239069). … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:21422162, PubMed:34239069, PubMed:8380639, PubMed:8384716).
Polypeptides: 5-hydroxytryptamine receptor 1FSynonyms: Serotonin receptor 1F5-hydroxytryptamine receptor 1E
go.drugbank.com/bio_entities/BE0000476TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:14744596, PubMed:1513320, PubMed:1608964, PubMed:1733778, PubMed:21422162, PubMed:33762731). … Also functions as a receptor for various alkaloids and psychoactive substances (PubMed:14744596, PubMed:1513320, PubMed:1608964, PubMed:1733778, PubMed:21422162, PubMed:33762731).
Polypeptides: 5-hydroxytryptamine receptor 1ESynonyms: Serotonin receptor 1ELow-density lipoprotein receptor
go.drugbank.com/bio_entities/BE0000499TargetCarrierHumansIn order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Polypeptides: Low-density lipoprotein receptorSynonyms: LDL receptorExtracellular calcium-sensing receptor
go.drugbank.com/bio_entities/BE0000509TargetHumansfull receptor activation (PubMed:27386547, PubMed:27434672, PubMed:32817431, PubMed:33603117, PubMed:34194040). … G protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (PubMed:17555508, PubMed:19789209, PubMed:21566075
Polypeptides: Extracellular calcium-sensing receptorSynonyms: Parathyroid cell calcium-sensing receptor 15-hydroxytryptamine receptor 2C
go.drugbank.com/bio_entities/BE0000533TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773). … Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)
Polypeptides: 5-hydroxytryptamine receptor 2CSynonyms: Serotonin receptor 2C, 5-hydroxytryptamine receptor 1CAlpha-1B adrenergic receptor
go.drugbank.com/bio_entities/BE0000575TargetHumansAlpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). Upon activation, they stimulate the phosphatidylinositol-calcium second messenge...
Polypeptides: Alpha-1B adrenergic receptorFunction: alpha1-adrenergic receptor activityProstaglandin F2-alpha receptor
go.drugbank.com/bio_entities/BE0000610TargetHumansReceptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. … Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor
Polypeptides: Prostaglandin F2-alpha receptorSynonyms: PGF receptor, PGF2-alpha receptor5-hydroxytryptamine receptor 7
go.drugbank.com/bio_entities/BE0000650TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:8226867).
Polypeptides: 5-hydroxytryptamine receptor 7Synonyms: Serotonin receptor 7Beta-2 adrenergic receptor
go.drugbank.com/bio_entities/BE0000694TargetHumansG protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, activating bifurcated signaling pathways (PubMed:2831218, PubMed:7915137).
Polypeptides: Beta-2 adrenergic receptor