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Displaying results 761 - 770 of 10000 in total
  1. Target

    Leukotriene C4 synthase

    go.drugbank.com/bio_entities/BE0001117
    TargetHumans

    Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator

    Synonyms: Glutathione S-transferase LTC4
  2. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes.

    Mixtures: AFTOJEL % 0,1 + %3 JEL (5 G), Innoprax-5Categories: Cyclooxygenase-2 (COX-2) Inhibitors, P-glycoprotein inducers
  3. Indication

    Erectile Dysfunction

    go.drugbank.com/conditions/DBCOND0029956
    Drugs: Alprostadil · Avanafil · Sildenafil · Tadalafil · Udenafil · Vardenafil
  4. Target

    Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase

    go.drugbank.com/bio_entities/BE0001402
    TargetVACV

    Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the...

    Synonyms: PAP-S
  5. Target

    Uroporphyrinogen-III C-methyltransferase

    go.drugbank.com/bio_entities/BE0002528
    TargetPseudomonas denitrificans

    Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1. It is a step in the biosynthesis of both cobalamin (vitamin B...

    Synonyms: S-adenosyl-L-methionine:uroporphyrinogen III methyltransferase
  6. Target

    Lactoylglutathione lyase

    go.drugbank.com/bio_entities/BE0000962
    TargetEnzymeHumans

    Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294).

    Synonyms: S-D-lactoylglutathione methylglyoxal lyase
  7. Target

    Hydroxymycolate synthase MmaA4

    go.drugbank.com/bio_entities/BE0003863
    TargetMycobacterium tuberculosis

    Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  8. Indication

    Primary Immune Deficiency Disorders (PIDD)

    go.drugbank.com/conditions/DBCOND0038807
    Drugs: Hyaluronidase (human recombinant)
    Synonyms: Primary Immunodeficiency Disease(s)
  9. Target

    Cyanocobalamin reductase / alkylcobalamin dealkylase

    go.drugbank.com/bio_entities/BE0002175
    TargetHumans

    Cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...

    Synonyms: Alkylcobalamin:glutathione S-alkyltransferase
  10. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.

    Mixtures: CLAMOXIN S, LUMOXBRON-SCategories: Penicillin G, Heterocyclic Compounds, 1-Ring