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Displaying results 7701 - 7710 of 10000 in total
  1. Target

    Gap junction delta-2 protein

    go.drugbank.com/bio_entities/BE0023585
    TargetHumans

    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell

    Polypeptides: Gap junction delta-2 protein
  2. Target

    Beta (β)-2 integrin (ITGB2)

    go.drugbank.com/bio_entities/BE0027979
    TargetHumans

  3. Target

    Cationic amino acid transporter 2

    go.drugbank.com/bio_entities/BE0000562
    TargetTransporterHumans

    Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:286847...

    Polypeptides: Cationic amino acid transporter 2Synonyms: CAT-2, Solute carrier family 7 member 2
  4. Target

    Interleukin-2 receptor subunit beta

    go.drugbank.com/bio_entities/BE0000651
    TargetHumans

    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

    Polypeptides: Interleukin-2 receptor subunit betaSynonyms: IL-2 receptor subunit beta, High affinity IL-2 receptor subunit beta
  5. Target

    C-C motif chemokine 2

    go.drugbank.com/bio_entities/BE0001047
    TargetHumans

    Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions ...

    Polypeptides: C-C motif chemokine 2
  6. Target

    Glutathione S-transferase Mu 2

    go.drugbank.com/bio_entities/BE0001189
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276)

    Polypeptides: Glutathione S-transferase Mu 2Synonyms: GSTM2-2, GST class-mu 2
  7. Target

    UDP-N-acetylglucosamine 2-epimerase

    go.drugbank.com/bio_entities/BE0001428
    TargetEscherichia coli (strain K12)

    Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.

    Polypeptides: UDP-N-acetylglucosamine 2-epimeraseSynonyms: UDP-GlcNAc-2-epimerase
  8. Target

    Glucose-6-phosphate isomerase 2

    go.drugbank.com/bio_entities/BE0001469
    TargetGeobacillus stearothermophilus

    Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.

    Polypeptides: Glucose-6-phosphate isomerase 2Synonyms: GPI 2, PGI 2
  9. Target

    3-methyl-2-oxobutanoate hydroxymethyltransferase

    go.drugbank.com/bio_entities/BE0001744
    TargetEscherichia coli (strain K12)

    Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

    Polypeptides: 3-methyl-2-oxobutanoate hydroxymethyltransferaseFunction: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
  10. Target

    TGF-beta receptor type-2

    go.drugbank.com/bio_entities/BE0001861
    TargetHumans

    The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and activation of TGFBR1 by the constitutively

    Polypeptides: TGF-beta receptor type-2Synonyms: TGFR-2