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Displaying results 7821 - 7830 of 10000 in total
  1. Target

    Beta-secretase 1

    go.drugbank.com/bio_entities/BE0000988
    TargetHumans

    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-c...

    Polypeptides: Beta-secretase 1Synonyms: Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1
  2. Target

    Clavaminate synthase 1

    go.drugbank.com/bio_entities/BE0001314
    TargetStreptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)

    Polypeptides: Clavaminate synthase 1Synonyms: Clavaminic acid synthase 1
  3. Target

    Glucose-1-phosphatase

    go.drugbank.com/bio_entities/BE0001703
    TargetEscherichia coli (strain K12)

    Absolutely required for the growth of E.coli in a high-phosphate medium containing G-1-P as the sole carbon source.

    Polypeptides: Glucose-1-phosphatase
  4. Target

    Serine protease 1

    go.drugbank.com/bio_entities/BE0001739
    TargetEnzymeHumans

    Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates

    Polypeptides: Serine protease 1Synonyms: Trypsin-1
  5. Target

    Formate acetyltransferase 1

    go.drugbank.com/bio_entities/BE0001741
    TargetEscherichia coli (strain K12)

    Catalyzes the conversion of pyruvate to formate and acetyl-CoA (PubMed:4615902). In addition, may be involved in the control of the activity of the formate channel FocA, via direct interaction with FocA (PubMed:24887098).

    Polypeptides: Formate acetyltransferase 1Synonyms: Pyruvate formate-lyase 1
  6. Target

    DNA topoisomerase 1

    go.drugbank.com/bio_entities/BE0001950
    TargetEscherichia coli (strain K12)

    The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

    Polypeptides: DNA topoisomerase 1
  7. Target

    Choline/ethanolaminephosphotransferase 1

    go.drugbank.com/bio_entities/BE0002190
    EnzymeHumans

    Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively (PubMed:10191259, PubMed:10893425, PubMed:12216837, PubMed:37137909). Involved in protein-dependent process ...

    Polypeptides: Choline/ethanolaminephosphotransferase 1Synonyms: 1-alkenyl-2-acylglycerol choline phosphotransferase
  8. Target

    FEZ-1 protein

    go.drugbank.com/bio_entities/BE0002693
    TargetFluoribacter gormanii

    Polypeptides: FEZ-1 protein
  9. Target

    1-phosphatidylinositol phosphodiesterase

    go.drugbank.com/bio_entities/BE0002943
    TargetListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

    Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Important factor in pathogenesis, PI-PLC activity is present only in virulent listeria species. It may participate in the lysis of th...

    Polypeptides: 1-phosphatidylinositol phosphodiesterase
  10. Target

    Angiopoietin-1 receptor

    go.drugbank.com/bio_entities/BE0003379
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskel...

    Polypeptides: Angiopoietin-1 receptor