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Peptidyl-prolyl cis-trans isomerase B
go.drugbank.com/bio_entities/BE0002332TargetHumansPeptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding
Synonyms: S-cyclophilinPurine nucleoside phosphorylase
go.drugbank.com/bio_entities/BE0003172TargetPlasmodium falciparum (isolate 3D7)Also catalyzes the phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine; MTI is produced by adenosine deaminase (ADA)-mediated breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product
Synonyms: S-methyl-5'-thioinosine phosphorylaseCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalVitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation
Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-DLeukotriene C4 synthase
go.drugbank.com/bio_entities/BE0001117TargetHumansCan also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator
Synonyms: Glutathione S-transferase LTC4Diclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes.
Mixtures: AFTOJEL % 0,1 + %3 JEL (5 G), Innoprax-5Categories: Cyclooxygenase-2 (COX-2) Inhibitors, P-glycoprotein inducersCap-specific mRNA (nucleoside-2'-O-)-methyltransferase
go.drugbank.com/bio_entities/BE0001402TargetVACVDisplays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the...
Synonyms: PAP-SUroporphyrinogen-III C-methyltransferase
go.drugbank.com/bio_entities/BE0002528TargetPseudomonas denitrificansCatalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1. It is a step in the biosynthesis of both cobalamin (vitamin B...
Synonyms: S-adenosyl-L-methionine:uroporphyrinogen III methyltransferaseLatanoprostene bunod
go.drugbank.com/drugs/DB11660ApprovedAs of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle glaucoma … Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure.
Lactoylglutathione lyase
go.drugbank.com/bio_entities/BE0000962TargetEnzymeHumansCatalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294).
Synonyms: S-D-lactoylglutathione methylglyoxal lyaseBrinzolamide
go.drugbank.com/drugs/DB01194Approved[L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320] … Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma.
Mixtures: BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, BRIDINE®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates