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Displaying results 71 - 80 of 5418 in total
  1. Target

    Laminin subunit alpha-1

    go.drugbank.com/bio_entities/BE0002108
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a li...

    Synonyms: S-LAM alpha, S-laminin subunit alpha
  2. Target

    Complement C1s subcomponent

    go.drugbank.com/bio_entities/BE0001529
    TargetEnzymeHumans

    Component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the ...

    Synonyms: Complement component 1 subcomponent s
  3. Target

    Vitronectin

    go.drugbank.com/bio_entities/BE0001068
    TargetHumans

    Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adh...

    Synonyms: S-protein
  4. Target

    Anamorsin

    go.drugbank.com/bio_entities/BE0015312
    TargetHumans

    Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. … Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.

    Synonyms: Fe-S cluster assembly protein DRE2 homolog
  5. Target

    Cytochrome P450 2C9

    go.drugbank.com/bio_entities/BE0002793
    TargetEnzymeHumans

    Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol (PubMed:11950794). … Contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan (PubMed:25994031)

    Synonyms: (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase
  6. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0003776
    TargetMycobacterium tuberculosis

    May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  7. Target

    Maleylacetoacetate isomerase

    go.drugbank.com/bio_entities/BE0000819
    TargetEnzymeHumans

    Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Also has low glutathione peroxidase activity with T-butyl and...

    Synonyms: Glutathione S-transferase zeta 1
  8. Target

    Adenosine deaminase

    go.drugbank.com/bio_entities/BE0009226
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741, PubMed:31002765). Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine bio...

    Synonyms: S-methyl-5'-thioadenosine deaminase
  9. Target

    Purine nucleoside phosphorylase

    go.drugbank.com/bio_entities/BE0003172
    TargetPlasmodium falciparum (isolate 3D7)

    Also catalyzes the phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine; MTI is produced by adenosine deaminase (ADA)-mediated breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product

    Synonyms: S-methyl-5'-thioinosine phosphorylase
  10. Target

    Leukotriene C4 synthase

    go.drugbank.com/bio_entities/BE0001117
    TargetHumans

    Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator

    Synonyms: Glutathione S-transferase LTC4