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Cytokine receptor-like factor 2
go.drugbank.com/bio_entities/BE0010586TargetHumansReceptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5.
Polypeptides: Cytokine receptor-like factor 2Synonyms: TSLP receptor, Cytokine receptor-like 2Interleukin-31 receptor subunit alpha
go.drugbank.com/bio_entities/BE0011013TargetHumansIn addition, the IL31 receptor complex activates the MAPK pathway (MAPK3/ERK1-MAPK1/ERK2) via recruitment of the adapter protein SHC1 (PubMed:15194700, PubMed:15627637). … Functions as a membrane-bound signal-transducing subunit of the IL31 receptor complex (heterodimer composed of OSMR and IL31RA) which binds IL31 (PubMed:15184896, PubMed:15194700, PubMed:15627637).
Polypeptides: Interleukin-31 receptor subunit alphaSynonyms: IL-31 receptor A, Gp130-like receptorVasoactive intestinal polypeptide receptor 1
go.drugbank.com/bio_entities/BE0013137TargetHumansG protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:35477937, PubMed:36385145, PubMed
Polypeptides: Vasoactive intestinal polypeptide receptor 1Synonyms: VPAC1 receptor, PACAP type II receptorGDNF family receptor alpha-1
go.drugbank.com/bio_entities/BE0013583TargetHumansGDNF-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977)
Polypeptides: GDNF family receptor alpha-1Synonyms: GDNF receptor alpha-1, TGF-beta-related neurotrophic factor receptor 1Corticotropin-releasing hormone receptor 2
go.drugbank.com/bio_entities/BE0014244TargetHumansG protein-coupled receptor for CRH, UCN, UCN2 and UCN3 stress hormones, which plays a central role in whole body adaptation to stress (PubMed:11329063, PubMed:11416224, PubMed:20966082, PubMed:22689579
Polypeptides: Corticotropin-releasing hormone receptor 2Synonyms: Corticotropin-releasing factor receptor 2Interleukin-10 receptor subunit alpha
go.drugbank.com/bio_entities/BE0014391TargetHumansCell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.
Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1G protein-coupled receptor 68
go.drugbank.com/bio_entities/BE0014724TargetHumansThe receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (PubMed:12955148, PubMed:39753132). … Proton-sensing G protein-coupled receptor activated by extracellular pH, which is required to monitor pH changes and generate adaptive reactions (PubMed:12955148, PubMed:29677517, PubMed:32865988, PubMed
Polypeptides: G protein-coupled receptor 68Synonyms: G protein-coupled receptor 12A, Ovarian cancer G protein-coupled receptor 1G protein-coupled receptor 84
go.drugbank.com/bio_entities/BE0020007TargetHumansG protein-coupled receptor that responds endogenously to dietary fatty acids or nutrient, specifically medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. … In immune cells, functions as a pro-inflammatory receptor via 6-OAU and promotes the expression of pro-inflammatory mediators such as TNFalpha, IL-6 and IL-12B as well as stimulating chemotactic responses
Polypeptides: G protein-coupled receptor 84Synonyms: Inflammation-related G protein-coupled receptor EX33Cefaloridine
go.drugbank.com/drugs/DB09008ApprovedWithdrawnIt is derived from cephalosporin C and is a zwitterion at physiological pH.
Lactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedA normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and ...
Mixtures: COMBINACIÓN PI, DIANEAL PD-1 with Dextrose