Search

Displaying results 791 - 800 of 2674 in total
  1. Target

    Interleukin-2 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0000658
    TargetHumans

    Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.

    Polypeptides: Interleukin-2 receptor subunit alphaSynonyms: IL-2 receptor subunit alpha
  2. Target

    Interferon alpha/beta receptor 1

    go.drugbank.com/bio_entities/BE0000661
    TargetHumans

    Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa) (PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:2153461 … Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity)

    Polypeptides: Interferon alpha/beta receptor 1Synonyms: IFN-alpha/beta receptor 1, Type I interferon receptor 1
  3. Target

    Retinoic acid receptor RXR-gamma

    go.drugbank.com/bio_entities/BE0000707
    TargetHumans

    Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor RXR-gammaSynonyms: Retinoid X receptor gamma, Nuclear receptor subfamily 2 group B member 3
  4. Target

    Glycine receptor subunit alpha-2

    go.drugbank.com/bio_entities/BE0000745
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:15302677, PubMed:16144831, PubMed:2155780, PubMed:23895467, PubMed:25445488, PubMed:26370147, PubMed:34473954). Plays a role in synaptic plasticity (By similarity). Contribut...

    Polypeptides: Glycine receptor subunit alpha-2
  5. Target

    Ephrin type-A receptor 2

    go.drugbank.com/bio_entities/BE0000841
    TargetHumans

    The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. … Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

    Polypeptides: Ephrin type-A receptor 2Synonyms: Tyrosine-protein kinase receptor ECK
  6. Target

    Receptor activity-modifying protein 2

    go.drugbank.com/bio_entities/BE0000860
    TargetHumans

    Together with CALCR, act as a receptor complex for calcitonin/CT/CALC (PubMed:35324283). Together with CALCR, also act as a receptor complex for amylin/IAPP (PubMed:35324283) … Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed

    Polypeptides: Receptor activity-modifying protein 2Synonyms: Calcitonin-receptor-like receptor activity-modifying protein 2
  7. Target

    Interleukin-3 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0001036
    TargetHumans

    Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted

    Polypeptides: Interleukin-3 receptor subunit alphaSynonyms: IL-3 receptor subunit alpha
  8. Target

    Gastrin/cholecystokinin type B receptor

    go.drugbank.com/bio_entities/BE0001158
    TargetHumans

    Receptor for the peptide hormones gastrin and cholecystokinin (CCK).

    Polypeptides: Gastrin/cholecystokinin type B receptorSynonyms: CCK-B receptor, Cholecystokinin-2 receptor
  9. Target

    Fibroblast growth factor receptor 4

    go.drugbank.com/bio_entities/BE0001203
    TargetHumans

    FGFR4 signaling is down-regulated by receptor internalization and degradation; MMP14 promotes internalization and degradation of FGFR4. … Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of

    Polypeptides: Fibroblast growth factor receptor 4
  10. Target

    Neuropeptide Y receptor type 2

    go.drugbank.com/bio_entities/BE0002419
    TargetHumans

    Receptor activation by ligands also leads to an increase of intracellular Ca(2+) levels (PubMed:7559383, PubMed:7592910). … Receptor for neuropeptide Y (NPY) and peptide YY (PYY) (PubMed:7592910, PubMed:7559383, PubMed:35507650, PubMed:36525977, PubMed:38882210).

    Polypeptides: Neuropeptide Y receptor type 2Synonyms: Y2 receptor, NPY-Y2 receptor