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Displaying results 811 - 820 of 10000 in total
  1. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.

    Mixtures: Cellmov Cell Line Mask, Mizon Black Snail All In One Crea MCategories: Antiarrhythmics, Class V, Heterocyclic Compounds, 2-Ring
  2. Drug

    Insulin detemir

    go.drugbank.com/drugs/DB01307
    ApprovedInvestigational

    [A2358, A2359, A2360, A44] If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis … [A2358, A2359, A2360, A44] Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that is a slowly progressing metabolic disorder caused by a combination of genetic

    Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: Levemir FlexPen 100U/ML Solution for injection in a prefilled pen, Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen
  3. Indication

    In a psychosocial support program

    go.drugbank.com/conditions/DBCOND0137015
    Drugs: Acamprosate
    Synonyms: In a psychosocial support program
  4. Drug

    Etevritamab

    go.drugbank.com/drugs/DB17211
    Investigational

    Synonyms: LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN A, anti-EGFRvIII x anti-CD3 bispecific T cell engager antibody construct
  5. Drug

    Magnesium

    go.drugbank.com/drugs/DB14513
    ApprovedInvestigational

    [A19349] The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. … [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559]

    Mixtures: BION 3 FILM COATED TABLET, One A Day TabProducts: MAGNEROT A 500 BEUTEL, MAGNEROT A 120 KAUTABL
  6. Drug

    Hyaluronidase

    go.drugbank.com/drugs/DB14740
    ApprovedInvestigational

    [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue. … [A199047] Hyaluronidase was first used in prescription products in the United States on 5 May 2004.[L13338]

    Products: HYLASE® DESSAU 150 IU, POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION PARA ADMINISTRACIÓN OFTALMICA
  7. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    It is also used as a coagulant in the water purification process. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

    Mixtures: KURSEPT %19 + %1 KREM (30 G), PERS-MANT %19 + %2 JEL (30 G)Products: Secret Dry Fresh Linen, A Bille
  8. Pathway

    The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria

    smpdb.ca/view/SMP0002358
    Disease

    L-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies. … This results in modulations of HIF-mediated hypoxia responses and alterations in gene expression through global epigenetic remodelling that may contribute to malignant transformation.

    Drugs: Pyruvic acid · Biotin · L-Glutamine · Succinic acid · Glutamic acid · NADH +6 more
  9. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent. … [A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.

    Mixtures: Combivent nebuliser solution in unit dose vial, Duovent Nebuliser solution in Unit Dose Vial 4mlSynonyms: Ipratropium ion
  10. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    [A180613, A180616, A180625] These other low‐potency antipsychotics are limited by their lower affinity for dopamine receptors, which requires a higher dose to effectively treat symptoms of schizophrenia … In addition, they block many receptors other than the primary target (dopamine receptors), such as cholinergic or histaminergic receptors, resulting in a higher incidence of side effects such as sedation

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one