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Displaying results 811 - 820 of 10000 in total
  1. Pathway

    Salsalate Action Pathway (New)

    smpdb.ca/view/SMP0126583
    Drug action

    Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.

    Drugs: Glutathione · Dinoprostone · Calcium · Salsalate · Mesoheme · Prostaglandin G2 +1 more
    Enzymes: Prostaglandin E synthase
  2. Drug

    Olive oil

    go.drugbank.com/drugs/DB09567
    ApprovedInvestigational

    Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].

    Mixtures: NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 ML, NUMETA PED G16 % E İNFÜZYONLUK EMÜLSİYON, 500 MLProducts: MediORO W, Intensive Treatment Bodyoil for Mommy To Be All Skin
  3. Target

    Endothelial PAS domain-containing protein 1

    go.drugbank.com/bio_entities/BE0009679
    TargetHumans

    Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). ...

    Synonyms: Class E basic helix-loop-helix protein 73
  4. Drug

    Ferrous bisglycinate

    go.drugbank.com/drugs/DB11210
    Approved

    Ferrous bisglycinate is a chelate that is used as a source of dietary iron. … Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional [A27250].

    Mixtures: PR Natal 430 ec, PR Natal 400 ec
  5. Drug

    Omega-3 fatty acids

    go.drugbank.com/drugs/DB11133
    ApprovedInvestigationalNutraceutical

    Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. … Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S.

    Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: Nutriflex Omega peri B. Braun Emulsion zur Infusion, PR Natal 430 ec
  6. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).

    Mixtures: DESLAIR® - D, DESLODEX ® D CÁPSULASCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-Ring
  7. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label].

    Mixtures: PRESSURISED INHALATION, SUSPENSION 50 MICROGRAM/5 MICROGRAM PER ACTUATION, PRESSURISED INHALATION, SUSPENSION 125 MICROGRAM/5 MICROGRAM PER ACTUATIONCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  8. Drug

    Obinutuzumab

    go.drugbank.com/drugs/DB08935
    ApprovedInvestigational

    [L54521] Like other drugs in its class, obinutuzumab targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes, mediating B-cell lysis. … Obinutuzumab is a humanized anti-CD20 monoclonal antibody designed to treat B-cell malignancies.

    Products: GAZYVA 1000 MG IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 ML
  9. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    [A174124] Valsartan is generally well-tolerated with a side-effect profile superior to that of other antihypertensive drugs.[A174130,A174133] … ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.

    Mixtures: VALSARTAN COMP PUR 80/12.5, VALSARTAN COMP PUR 80/12.5Categories: Angiotensin 2 Receptor Blocker, Cytochrome P-450 Substrates
  10. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment

    Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCategories: 5-alpha Reductase Inhibitors, Cytochrome P-450 Substrates