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Displaying results 811 - 820 of 10000 in total
  1. Target

    Insulin receptor-related protein

    go.drugbank.com/bio_entities/BE0009451
    TargetHumans

    Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH.

    Polypeptides: Insulin receptor-related proteinSynonyms: IR-related receptor
  2. Target

    5-hydroxytryptamine receptor 3B

    go.drugbank.com/bio_entities/BE0009583
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3BSynonyms: Serotonin receptor 3B
  3. Target

    5-hydroxytryptamine receptor 3E

    go.drugbank.com/bio_entities/BE0009586
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3ESynonyms: Serotonin receptor 3E
  4. Target

    CX3C chemokine receptor 1

    go.drugbank.com/bio_entities/BE0010049
    TargetHumans

    Also acts as a receptor for C-C motif chemokine CCL26, inducing cell chemotaxis (PubMed:20974991) … Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells; CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response

    Polypeptides: CX3C chemokine receptor 1Synonyms: Fractalkine receptor, Beta chemokine receptor-like 1
  5. Target

    Proteinase-activated receptor 2

    go.drugbank.com/bio_entities/BE0010726
    TargetHumans

    Receptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455). … Believed to be a class B receptor which internalizes as a complex with arrestin and traffic with it to endosomal vesicles, presumably as desensitized receptor, for extended periods of time.

    Polypeptides: Proteinase-activated receptor 2Synonyms: Thrombin receptor-like 1, G protein-coupled receptor 11
  6. Target

    Gastric inhibitory polypeptide receptor

    go.drugbank.com/bio_entities/BE0011012
    TargetHumans

    This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

    Polypeptides: Gastric inhibitory polypeptide receptorSynonyms: Glucose-dependent insulinotropic polypeptide receptor
  7. Target

    Toll-like receptor 5

    go.drugbank.com/bio_entities/BE0011820
    TargetHumans

    Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781).

    Polypeptides: Toll-like receptor 5Synonyms: Toll/interleukin-1 receptor-like protein 3
  8. Target

    Complement receptor type 1

    go.drugbank.com/bio_entities/BE0012722
    TargetHumans

    Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069).

    Polypeptides: Complement receptor type 1Synonyms: C3b/C4b receptor
  9. Target

    Neurotensin receptor type 1

    go.drugbank.com/bio_entities/BE0013004
    TargetHumans

    G protein-coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:21725197, PubMed:23140271, PubMed:8381365).

    Polypeptides: Neurotensin receptor type 1Synonyms: High-affinity levocabastine-insensitive neurotensin receptor
  10. Target

    Bombesin receptor subtype-3

    go.drugbank.com/bio_entities/BE0013148
    TargetHumans

    This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: Bombesin receptor subtype-3Function: bombesin receptor activity