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Displaying results 811 - 820 of 1203 in total
  1. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.

    Mixtures: Revit Multi-vitamins and Minerals
  2. Target

    Vascular endothelial growth factor receptor 3

    go.drugbank.com/bio_entities/BE0000023
    TargetHumans

    The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. … Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular

    Polypeptides: Vascular endothelial growth factor receptor 3Synonyms: Tyrosine-protein kinase receptor FLT4
  3. Target

    Receptor-type tyrosine-protein kinase FLT3

    go.drugbank.com/bio_entities/BE0000147
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells.

    Polypeptides: Receptor-type tyrosine-protein kinase FLT3Synonyms: FL cytokine receptor
  4. Target

    Sigma non-opioid intracellular receptor 1

    go.drugbank.com/bio_entities/BE0000290
    TargetHumans

    Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the...

    Polypeptides: Sigma non-opioid intracellular receptor 1Synonyms: Sigma 1-type opioid receptor, Sigma non-opioid intracellular receptor 1
  5. Target

    Vascular endothelial growth factor receptor 2

    go.drugbank.com/bio_entities/BE0000369
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD.

    Polypeptides: Vascular endothelial growth factor receptor 2Synonyms: Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1
  6. Target

    Taste receptor type 1 member 2

    go.drugbank.com/bio_entities/BE0000395
    TargetHumans

    Key component of the sweet taste receptor (PubMed:11917125, PubMed:40339580, PubMed:40754567, PubMed:40555359). … Functions as a G protein-coupled receptor and primarily signals through the gustducin heterotrimer (PubMed:40339580)

    Polypeptides: Taste receptor type 1 member 2Synonyms: Sweet taste receptor T1R2, G protein-coupled receptor 71
  7. Target

    Neuronal acetylcholine receptor subunit beta-2

    go.drugbank.com/bio_entities/BE0000850
    TargetHumans

    Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collecti...

    Polypeptides: Neuronal acetylcholine receptor subunit beta-2
  8. Target

    Platelet-derived growth factor receptor alpha

    go.drugbank.com/bio_entities/BE0000852
    TargetEnzymeHumans

    Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor … Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis

    Polypeptides: Platelet-derived growth factor receptor alphaSynonyms: Alpha platelet-derived growth factor receptor, Platelet-derived growth factor receptor 2
  9. Target

    Macrophage colony-stimulating factor 1 receptor

    go.drugbank.com/bio_entities/BE0000853
    TargetHumans

    Receptor signaling is down-regulated by protein phosphatases, such as INPP5D/SHIP-1, that dephosphorylate the receptor and its downstream effectors, and by rapid internalization of the activated receptor … Tyrosine-protein kinase that acts as a cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells

    Polypeptides: Macrophage colony-stimulating factor 1 receptorSynonyms: CSF-1 receptor
  10. Target

    Epithelial discoidin domain-containing receptor 1

    go.drugbank.com/bio_entities/BE0001124
    TargetHumans

    Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation

    Polypeptides: Epithelial discoidin domain-containing receptor 1Synonyms: Discoidin receptor tyrosine kinase, Epithelial discoidin domain receptor 1