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Carbamoyl-phosphate synthase [ammonia], mitochondrial
go.drugbank.com/bio_entities/BE0004671TargetEnzymeHumansInvolved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell
Synonyms: CPSase I, Carbamoyl-phosphate synthetase IDeoxyribonuclease-1
go.drugbank.com/bio_entities/BE0012829TargetHumansSerum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:11241278, PubMed:2251263, PubMed:2277032). Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By sim...
Synonyms: DNase I, Deoxyribonuclease IFunction: deoxyribonuclease I activityClassical Hodgkin's Lymphoma
go.drugbank.com/conditions/DBCOND0113588Synonyms: Hodgkin lymphoma, no ICD-O subtype, Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)Perindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration.
Mixtures: COVERATRIX 5 MG/1.25 MG/10 MG COMPRIMIDOS RECUBIERTOS CON PELÍCULA, COVERATRIX 10 MG / 2.5 MG / 5 MG COMPRIMIDOS RECUBIERTOS CON PELÍCULACategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalIt belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the … [A181409,A181535,A181538,A1793] Potency is thought to correlate to tissue permeability as the more lipophilic statins such as simvastatin are thought to enter endothelial cells by passive diffusion, as
Mixtures: TIAZOMET S®, TIAZOMET S®Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSerine protease 1
go.drugbank.com/bio_entities/BE0001739TargetEnzymeHumansHas activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates
Synonyms: Trypsin I, Anionic trypsin IMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAn anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. … In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and interest in the agent's capacity to decrease inflammatory activity and subsequently potentially reduce
Categories: Analgesics, Non-NarcoticSynonyms: 3-carboxy-4-hydroxyaniline, 5-ASAAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959]. … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: ALENDRON-HEXAL 4 WO CAL D, ALENDRON-HEXAL 12 WO CAL DSynonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acidPrizloncabtagene autoleucel
go.drugbank.com/drugs/DB18623InvestigationalC-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Synonyms: autologous T lymphocytes obtained from peripheral blood lymphocytes by leukapheresis, transduced with a self-inactivating, non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor, an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR