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Acetyl-coenzyme A synthetase
go.drugbank.com/bio_entities/BE0001916TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.
Polypeptides: Acetyl-coenzyme A synthetaseNucleoside diphosphate kinase A
go.drugbank.com/bio_entities/BE0003106TargetEnzymeHumansCatalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving a phosphohistidine intermediate, therefore … May also function as a Mg(2+)-dependent 3'-5' DNA exonuclease, excising nucleotides from 3' single-stranded DNA or DNA with 3' single strand overhangs, suggesting a role in DNA nucleolytic processing (
Polypeptides: Nucleoside diphosphate kinase ASynonyms: NDPK A, NDP kinase AStringent starvation protein A
go.drugbank.com/bio_entities/BE0003260TargetYersinia pestisPolypeptides: Stringent starvation protein ASynonyms: Putative stringent starvation protein A, Regulator of transcription stringent starvation protein APoly(A) polymerase alpha
go.drugbank.com/bio_entities/BE0004515TargetHumansMay acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus … Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.
Polypeptides: Poly(A) polymerase alphaDNA gyrase subunit A
go.drugbank.com/bio_entities/BE0008382TargetEscherichia coli (strain K12)A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to maintain chromosomes in an underwound state (PubMed:12051842, PubMed:18642932,
Polypeptides: DNA gyrase subunit ADNA gyrase subunit A
go.drugbank.com/bio_entities/BE0008385TargetStaphylococcus aureusA type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.
Polypeptides: DNA gyrase subunit ARepulsive guidance molecule A
go.drugbank.com/bio_entities/BE0018257TargetHumansIt also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8
Polypeptides: Repulsive guidance molecule ASynonyms: RGM domain family member APoly(A) polymerase gamma
go.drugbank.com/bio_entities/BE0018981TargetHumansResponsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA
Polypeptides: Poly(A) polymerase gammaSynonyms: Neo-poly(A) polymeraseLipid A palmitoyltransferase PagP
go.drugbank.com/bio_entities/BE0001965TargetEscherichia coli (strain K12)Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
Polypeptides: Lipid A palmitoyltransferase PagPSynonyms: Lipid A acylation proteinDihydroorotate dehydrogenase A (fumarate)
go.drugbank.com/bio_entities/BE0002008TargetLactococcus lactis subsp. cremorisCatalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD A