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Displaying results 871 - 880 of 10000 in total
  1. Pathway

    Acylcarnitine (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,13-tetraenoylcarnitine

    smpdb.ca/view/SMP0123561
    Metabolic

    Once inside the cell it undergoes a reaction to form an acyl-CoA derivative called (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,13-tetraenoyl-CoA. … This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Drug

    Technetium Tc-99m mebrofenin

    go.drugbank.com/drugs/DB09137
    ApprovedWithdrawn

    Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. … This is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium
  3. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904] … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors.

    Mixtures: ARTENSOL® H 40 MG TABLETASCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, P-glycoprotein inhibitors
  4. Drug

    Estriol

    go.drugbank.com/drugs/DB04573
    ApprovedInvestigationalVet approved

    A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. … It is however available in the United States by prescription filled only by compounding pharmacies.

    Synonyms: (16α,17β)-estra-1,3,5(10)-triene-3,16,17-triolInternational brands: Synapause E
  5. Target

    Chitinase A

    go.drugbank.com/bio_entities/BE0001649
    TargetSerratia marcescens

    Polypeptides: Chitinase A
  6. Target

    Gyrase A

    go.drugbank.com/bio_entities/BE0008384
    TargetMycobacterium tuberculosis

    Polypeptides: Gyrase A
  7. Target

    Cyclin A

    go.drugbank.com/bio_entities/BE0009669
    Target

  8. Target

    Proenkephalin-A

    go.drugbank.com/bio_entities/BE0010659
    TargetHumans

    They play a role in a number of physiologic functions, including pain perception and responses to stress

    Polypeptides: Proenkephalin-A
  9. Target

    Apolipoprotein(a)

    go.drugbank.com/bio_entities/BE0001283
    TargetHumans

    Lp(a) may be a ligand for megalin/Gp 330 … Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.

    Polypeptides: Apolipoprotein(a)Synonyms: Lp(a), Apo(a)
  10. Target

    Exotoxin A

    go.drugbank.com/bio_entities/BE0001869
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis (PubMed:18276581, PubMed:2170123). Ha...

    Polypeptides: Exotoxin A