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Antipyrine Action Pathway
smpdb.ca/view/SMP0000692Drug actionAntipyrine (also named Fenazone or Phenazone) is often used for testing the effect of other drugs on drug-metabolizing enzymes in the liver. Antipyrine can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H sy...
Antrafenine Action Pathway
smpdb.ca/view/SMP0000693Drug actionAntrafenine (also named Stakane) acts as an anti-inflammatory and analgesic drug. It is not widely used as it has largely been replaced by newer drugs. Antrafenine can block prostaglandin synthesis by the action of inhibition of prostagl...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Antrafenine +5 moreCarprofen Action Pathway
smpdb.ca/view/SMP0000694Drug actionCarprofen (also named Rimadyl or Imadyl) is a nonsteroidal anti-inflammatory drug that can treat various joint pain or post-operative pain. Carprofen can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synt...
Lumiracoxib Action Pathway
smpdb.ca/view/SMP0000699Drug actionLumiracoxib (also named Prexige) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used as the mediators of certain kinds of intraocular inflammation. Lumiracoxib can block prostaglandin synthesis by the action of inhibition of...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Lumiracoxib · Calcium · Magnesium cation +5 moreThe Oncogenic Action of 2-Hydroxyglutarate
smpdb.ca/view/SMP0002291Disease2-Hydroxyglutarate is a compound formed from isocitric acid, a component of the TCA cycle. Isocitric acid becomes dehydrogenated by isocitrate dehydrogenase using NADP as a cofactor, and forming oxoglutaric acid. Oxoglutaric acid then fo...
Quinapril ACE Inhibitor Action Pathway
smpdb.ca/view/SMP0123094Drug actionQuinapril is angiotensin-converting enzyme (ACE) inhibitor for the conversion of angiotensin I into angiotensin II. Angiotensin II is a critical circulating peptide hormone that has powerful vasoconstrictive effects and increases blood p...
Trandolapril ACE Inhibitor Action Pathway
smpdb.ca/view/SMP0123104Drug actionTrandolapril is an angiotensin-converting enzyme (ACE) inhibitor for the conversion of angiotensin I into angiotensin II. Angiotensin II is a critical circulating peptide hormone that has powerful vasoconstrictive effects and increases b...
Candesartan Action Pathway (New)
smpdb.ca/view/SMP0124964Drug actionCandesartan is angiotensin receptor blocker (ARB) which block the action of angiotensin II by binding to the type 1 angiotensin II receptor. Angiotensin II is a critical circulating peptide hormone that has powerful vasoconstrictive effe...
Olmesartan ARB Action Pathway
smpdb.ca/view/SMP0124968Drug actionOlmesartan is angiotensin receptor blocker (ARB) which block the action of angiotensin II by binding to the type 1 angiotensin II receptor. Angiotensin II is a critical circulating peptide hormone that has powerful vasoconstrictive effec...
Telmisartan Action Pathway (New)
smpdb.ca/view/SMP0124969Drug actionTelmisartan is angiotensin receptor blocker (ARB) which block the action of angiotensin II by binding to the type 1 angiotensin II receptor. Angiotensin II is a critical circulating peptide hormone that has powerful vasoconstrictive effe...