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Displaying results 81 - 90 of 390 in total
  1. Drug

    Indoramin

    go.drugbank.com/drugs/DB08950
    ApprovedWithdrawn

    Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese.

    International brands: Baratol
  2. Drug

    Rintatolimod

    go.drugbank.com/drugs/DB16425
    Investigational

    Synonyms: 5'-INOSINIC ACID, HOMOPOLYMER, COMPLEX WITH 5'-CYTIDYLIC ACID POLYMER WITH 5'-URIDYLIC ACID (1:1)
  3. Drug

    Tivanisiran

    go.drugbank.com/drugs/DB19105
    Investigational

    Tivanisiran is under investigation in clinical trial NCT03108664 (HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)).

    Synonyms: Rna, (a-a-g-c-g-c-a-u-c-u-u-c-u-a-c-u-u-c-a), complex with rna (u-g-a-a-g-u-a-g-a-a-g-a-u-g-c-g-c-u-u) (1:1)
  4. Drug

    Oteracil

    go.drugbank.com/drugs/DB03209
    ApprovedInvestigational

    The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells. … Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal mucosa, and therefore reduce's gastrointestinal toxicity [L933].

  5. Drug

    Denosumab

    go.drugbank.com/drugs/DB06643
    ApprovedInvestigational

    It further received additional indication approval to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for non-metastatic prostate cancer and women at high risk

    Categories: Complex Mixtures
  6. Drug

    Rimonabant

    go.drugbank.com/drugs/DB06155
    ApprovedWithdrawn

    Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world.

  7. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens. … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells.

  8. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    [A228183] Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and lipid

  9. Drug

    Brivoligide

    go.drugbank.com/drugs/DB16116
    Investigational

    Brivoligide is under investigation in clinical trial NCT04104919 (Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores).

    Synonyms: D(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1), Dna, d(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1)
  10. Drug

    Testosterone undecanoate

    go.drugbank.com/drugs/DB13946
    ApprovedInvestigational

    hypogonadism, resulting from insufficient testosterone secretion, can result symptoms and signs of testosterone deficiency, such as decreased libido, erectile dysfunction, and loss of muscle and bone mass