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Aromatic L-Aminoacid Decarboxylase Deficiency
smpdb.ca/view/SMP0000170DiseaseIt also results in decreased concentrations of homovanillic acid, S-adenosylmethionine, and 5-hydroxytryptophol in spinal fluid; and epinephrine, norepinephrine in plasma.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 moreTyrosine Hydroxylase Deficiency
smpdb.ca/view/SMP0000497DiseaseThis enzyme is part of the production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal nervous system function. … Norepinephrine and epinephrine are involved in the autonomic nervous system. Mutations in the TH gene result in reduced activity of the tyrosine hydroxylase enzyme.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 moreAromatic L-Aminoacid Decarboxylase Deficiency
smpdb.ca/view/SMP0125610DiseaseIt also results in decreased concentrations of homovanillic acid, S-adenosylmethionine, and 5-hydroxytryptophol in spinal fluid; and epinephrine, norepinephrine in plasma.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 moreTyrosine Hydroxylase Deficiency
smpdb.ca/view/SMP0125611DiseaseThis enzyme is part of the production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal nervous system function. … Norepinephrine and epinephrine are involved in the autonomic nervous system. Mutations in the TH gene result in reduced activity of the tyrosine hydroxylase enzyme.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 moreMaprotiline Action Pathway
smpdb.ca/view/SMP0126344Drug actionThis tetracyclic molecule strongly inhibits neuronal norepinephrine reuptake in the brain and peripheral tissues. … Maprotiline also inhibits the amine transporter, it causes delaying of the reuptake of noradrenaline and norepinephrine into neurons. This drug is administered as an oral tablets.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Sapropterin · Norepinephrine · Maprotiline +5 moreAtomoxetine Action Pathway (New)
smpdb.ca/view/SMP0126353Drug actionAtomoxetine, also known as Strattera, is a selective norepinephrine reuptake inhibitor (SNRI). It is used in the management of attention deficit hyperactivity disorder (ADHD). … In consequence, there is more norepinephrine available in the synapses and in the brain in general. This will increase the activation of alpha-adrenergic receptors in the postsynaptic neurons.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Atomoxetine · Sapropterin · Norepinephrine +5 moreMethyldopa Action Pathway
smpdb.ca/view/SMP0125087Drug actionLow concentration of calcium prevents the release of norepinephrine into the synapse.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Sapropterin · Norepinephrine · Dopamine +5 moreTrimipramine Action Pathway
smpdb.ca/view/SMP0126348Drug actionTrimipramine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT) in the neurons.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreCodeine Action Pathway
smpdb.ca/view/SMP0000405Drug actionOpiate receptors are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for...
Citalopram Action Pathway
smpdb.ca/view/SMP0000424Drug actionCitalopram is a selective serotonin reuptake inhibitor that exerts antidepressive effects by selectively inhibiting serotonin reuptake in the brain. It does so by competing for the same binding site as serotonin on the the sodium-depende...