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Displaying results 891 - 900 of 10000 in total
  1. Drug

    Biperiden

    go.drugbank.com/drugs/DB00810
    ApprovedInvestigationalWithdrawn

    It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine. … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism.

    Synonyms: 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanolProducts: AKINETON 2MG, Akineton Tab 2mg
  2. Drug

    Nateglinide

    go.drugbank.com/drugs/DB00731
    Approved

    The average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those naïve to oral antidiabetic agents. … Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing postprandial blood glucose levels.

    Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismProducts: Starlix 60mg, Starlix 120mg
  3. Drug

    Mebendazole

    go.drugbank.com/drugs/DB00643
    ApprovedInvestigationalVet approved

    A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]

    Categories: Antiparasitic Products, Insecticides and RepellentsProducts: QUEMOX TABLET 500MG, QUEMOX GRANULES 500MG
  4. Pathway

    D-Arginine and D-Ornithine Metabolism

    smpdb.ca/view/SMP0000036
    Metabolic

    D-Amino may have negative effects as they can be found in some bacteria or form spontaneously in certain reactions. … D-Amino acids have been show to be present in high concentrations in humans and play a role in biological functions.

    Drugs: 3,4-Dihydro-2h-Pyrrolium-5-Carboxylate · Flavin adenine dinucleotide · Urea
  5. Pathway

    Metabolism and Physiological Effects of Phenylacetylglutamine

    smpdb.ca/view/SMP0123208
    Metabolic

    Phenylacetylglutamine is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound. … Phenylacetylglutamine is a microbial metabolite found in Christensenellaceae, Lachnospiraceae and Ruminococcaceae.

    Drugs: Phenylalanine · L-Glutamine · Adenosine phosphate · ATP · Magnesium cation · Phenylpyruvic acid +1 more
  6. Pathway

    Metabolism and Physiological Effects of Phenol

    smpdb.ca/view/SMP0123255
    Metabolic

    Phenol can get further metabolized in a liver hepatocyte to Phenyl sulphate and Phenyl glucuronide. However phenol itself is shown to be a major uremic toxin through high levels of retention. … Phenol is shown to cause cardiovascular disease and enhance the production of reactive oxygen species and cause oxidative stress.

    Drugs: Tyrosine · Phenol
  7. Pathway

    Metabolism and Physiological Effects of Choline

    smpdb.ca/view/SMP0124739
    Metabolic

    The toxicity of choline is due to the formation of TMA and its metabolism to Trimethylamine N-oxide (TMAO) in the liver. … In the intestine, choline is metabolized to other products such as acetylcholine, betaine, phosphatidylcholine and trimethylamine (TMA) by the gut microbiota.

    Drugs: Choline · Flavin adenine dinucleotide
  8. Pathway

    Metabolism and Physiological Effects of Dimethylglycine

    smpdb.ca/view/SMP0124873
    Metabolic

    Dimethylglycine (DMG) is an amino acid derivative found in the cells of all plants and animals and can be obtained in the diet in small amounts from grains and meat. … Dimethylglycine enters the bloodstream and can cause toxic effects on the cardiovascular system.

    Drugs: Choline · Methionine · NADH · Zinc · N,N-dimethylglycine · Flavin adenine dinucleotide +1 more
  9. Pathway

    Metabolism and Physiological Effects of Phenylacetylglycine

    smpdb.ca/view/SMP0126858
    Metabolic

    In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. … Phenylacetic acid is used in some perfumes, possessing a honey-like odour in low concentrations, and is also used in penicillin G production. PAG is a putative biomarker of phospholipidosis.

    Drugs: Glycine
  10. Drug

    Saxagliptin

    go.drugbank.com/drugs/DB06335
    ApprovedInvestigational

    Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.

    Mixtures: KOMBIGLYZE XR TABLET 5MG/500MG, KOMBIGLYZE XR TABLET 5MG/1000MGCategories: Drugs Used in Diabetes, DPP-IV Inhibitors