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Displaying results 891 - 900 of 10000 in total
  1. Drug

    Racementhol

    go.drugbank.com/drugs/DB14123
    ApprovedInvestigational

    Mixtures: La Vaquita, Cho-a PAPSynonyms: p-Menthan-3-ol
  2. Indication

    Influenza A Virus Infection

    go.drugbank.com/conditions/DBCOND0036858
    Drugs: Amantadine · Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen · Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) · Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen · Influenza A virus A/New caledonia/71/2014 (H3N2) live (attenuated) antigen · Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) +3 more
    Synonyms: Influenza A, Influenza A H1N1
  3. Indication

    Influenza A, Influenza B

    go.drugbank.com/conditions/DBCOND0051432
    Drugs: Oseltamivir
    Synonyms: Influenza A,B, Influenza A, Influenza B
  4. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … [A33889] When used in large doses, dimenhydrinate has been shown to cause a "high" characterized by hallucinations, excitement, incoordination, and disorientation.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate
  5. Drug

    Pegfilgrastim

    go.drugbank.com/drugs/DB00019
    ApprovedInvestigational

    [L9974] NIOPEG (pegfilgrastim), a biosimilar of NEULASTA®, was approved by Health Canada in April 2024 for the prevention of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive … [A29,A187607] Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires less frequent dosing than filgrastim; however, pegfilgrastim has a comparable pharmacological

    Categories: Compounds used in a research, industrial, or household setting, Complex MixturesSynonyms: 吉新芬, PEG-G-CSF
  6. Drug

    Pralidoxime

    go.drugbank.com/drugs/DB00733
    ApprovedInvestigationalVet approved

    Pralidoxime is an antidote to organophosphate pesticides and chemicals. … If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-PAM
  7. Drug

    Citrus bioflavonoids

    go.drugbank.com/drugs/DB14586
    Approved

    Synonyms: Hesperidin complexMixtures: Nutriforte Non-Acidic Vitamin C 1000 mg with Bioflavonoids, NATURERICH ESTER-C COMPLEX TABLETS
  8. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and

    Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide, [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acidCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  9. Target

    Coagulation factor XIII A chain

    go.drugbank.com/bio_entities/BE0000004
    TargetEnzymeHumans

    Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot

    Polypeptides: Coagulation factor XIII A chainSynonyms: Transglutaminase A chain, Protein-glutamine gamma-glutamyltransferase A chain
  10. Target

    L-lactate dehydrogenase A chain

    go.drugbank.com/bio_entities/BE0000425
    TargetHumans

    Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)

    Polypeptides: L-lactate dehydrogenase A chainSynonyms: LDH-A