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Displaying results 901 - 910 of 10000 in total
  1. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    The option for single daily dosing of amlodipine is an attractive feature of this drug [FDA label]. … Amlodipine is commonly used in the treatment of high blood pressure and angina.

    Categories: Angiotensin II receptor blockers (ARBs) and calcium channel blockers, Angiotensin II Antagonists and Calcium Channel BlockersProducts: AMLODIPINA RK, Van-amlodipine
  2. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction. … [A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.

    Categories: Compounds used in a research, industrial, or household settingProducts: Lisinopril Tablets USP
  3. Drug

    Bilberry

    go.drugbank.com/drugs/DB14235
    ApprovedWithdrawn

    Synonyms: Myrtilli fructus recens (vaccinium myrtillus l.)
  4. Drug

    Inolimomab

    go.drugbank.com/drugs/DB15628
    Investigational

    Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385]

    Synonyms: Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain), disulfide with mouse monoclonal B-B10 kappa-chain, dimer
  5. Pathway

    Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

    smpdb.ca/view/SMP0000321
    Signaling

    The adenosine receptor A2b activates G(s) proteins which lead to the activation of adenylyl cyclase which produces the secondary messenger cAMP. cAMP activates PKA (protein kinase A) which phosphorylates

    Drugs: ATP · Adenosine · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Adenosine receptor A2b
  6. Indication

    Hypoestrogenism

    go.drugbank.com/conditions/DBCOND0020874
    Drugs: Androstenediol · Androstenedione · Conjugated estrogens · Estradiol · Estradiol benzoate · Estradiol cypionate +4 more
  7. Drug

    Mometasone furoate

    go.drugbank.com/drugs/DB14512
    ApprovedInvestigationalVet approved

    Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. … It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906].

    Products: Up and Up Allergy, K-MEXADER % 0.1 KREM
  8. Drug

    Batoclimab

    go.drugbank.com/drugs/DB16104
    Investigational

    Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).

    Synonyms: Immunoglobulin g1(238-alanine, 239-alanine), anti-(human fcrn receptor) (human monoclonal hl161bkn .gamma.1-chain), disulfide with human monoclonal hl161bkn .lambda.-chain, dimer
  9. Indication

    Primary Ovarian Insufficiency

    go.drugbank.com/conditions/DBCOND0000990
    Drugs: Esterified estrogens · Estradiol
  10. Drug

    Eplerenone

    go.drugbank.com/drugs/DB00700
    ApprovedInvestigational

    Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative

    Categories: Mineralocorticoid Receptor Antagonists, Mineralocorticoid (Aldosterone) Receptor AntagonistsProducts: INSPRA IC