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Bambuterol
go.drugbank.com/drugs/DB01408InvestigationalBambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
Synonyms: (±)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate)Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigationalTiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. … [A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than [ipratropium].
Mixtures: SPIOLTO®RESPIMAT®, SPIOLTO®RESPIMAT®Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingPranlukast
go.drugbank.com/drugs/DB01411InvestigationalPranlukast is a cysteinyl leukotriene receptor-1 antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsCefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigationalCefepime is a fourth-generation cephalosporin antibiotic developed in 1994. … [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical
Synonyms: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateCategories: Heterocyclic Compounds, 2-RingCeftibuten
go.drugbank.com/drugs/DB01415ApprovedInvestigationalCeftibuten is a third-generation cephalosporin antibiotic that is orally-administered. … It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Synonyms: (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acidMixtures: WINCEF PLUS 180/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, WINCEF PLUS 90/62.5 MG 5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLStepronin
go.drugbank.com/drugs/DB01423ExperimentalStrepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. … The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
Categories: Heterocyclic Compounds, 1-RingAminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnAminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. … The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
Synonyms: 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazoloneCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesAjmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnIt is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. … It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope.
Synonyms: (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b]quinolizine-8,13-diolCategories: Antiarrhythmics, Class I, Heterocyclic Compounds, 2-RingAprindine
go.drugbank.com/drugs/DB01429ExperimentalAprindine is a cardiac depressant used in arrhythmias.
Categories: Antiarrhythmics, Class I, Cytochrome P-450 Substrates3-Methylthiofentanyl
go.drugbank.com/drugs/DB01439ExperimentalIllicit3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.
Synonyms: 3-Methyl-thiofentanyl, 3-Methylthiofentanyl