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Displaying results 911 - 920 of 1994 in total
  1. Pathway

    Rosuvastatin

    smpdb.ca/view/SMP0124577
    Drug action

    Statins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it. … Reported side effects of Rosuvastatin include constipation, flatulence, dyspepsia (indigestion), abdominal pain, headache, and myalgia (muscle pain).

    Drugs: Rosuvastatin · Calcium · Zinc · Cholesterol
    Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 protease
  2. Pathway

    Simvastatin Action Pathway (New)

    smpdb.ca/view/SMP0124578
    Drug action

    Statins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it. … Reported side effects of Simvastatin include constipation, flatulence, dyspepsia (indigestion), abdominal pain, headache, and myalgia (muscle pain).

    Drugs: Simvastatin · Calcium · Zinc · Cholesterol
    Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 protease
  3. Indication

    Cutaneous Melanoma

    go.drugbank.com/conditions/DBCOND0040978
    Drugs: Ipilimumab
    Synonyms: Melanoma of skin, site unspecified
  4. Indication

    Melanoma

    go.drugbank.com/conditions/DBCOND0020306
    Drugs: Dabrafenib · Nivolumab · Peginterferon alfa-2b · Trametinib
    Synonyms: Melanoma of skin, site unspecified
  5. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ...

    Products: Suite Scrub Foam Liq 3%, Suite Scrub 1000 Liq 3%
  6. Drug

    Crotamiton

    go.drugbank.com/drugs/DB00265
    Approved

    Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.

    Products: A-Bite Cream
  7. Drug

    Sulfamethoxazole

    go.drugbank.com/drugs/DB01015
    ApprovedInvestigational

    Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic ac...

    Mixtures: COTRIM - CT 800MG/160MG, COTRIM - CT 800MG/160MGProducts: Sulfamethoxazole Tab 500mg, Apo Sulfamethoxazole Tab 500mg
  8. Drug

    Erdosteine

    go.drugbank.com/drugs/DB05057
    ApprovedInvestigational

    Erdosteine 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol

    Products: ERDOMED HARD CAPSULES 300MG, ERDOMED® Hard Capsules 300mg
  9. Drug

    Hexafluronium

    go.drugbank.com/drugs/DB00941
    Approved

    Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. It is known to bind and block the activity of plasma cholineste...

  10. Indication

    Poor Risk Advanced Renal Cell Cancer

    go.drugbank.com/conditions/DBCOND0145158
    Drugs: Hyaluronidase (human recombinant) · Nivolumab
    Synonyms: Poor Risk Advanced Renal Cell Cancer