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Displaying results 921 - 930 of 1994 in total
  1. Pathway

    Atorvastatin Action Pathway (New)

    smpdb.ca/view/SMP0124555
    Drug action

    Statins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it. … Reported side effects of atorvastatin include constipation, flatulence, dyspepsia (indigestion), abdominal pain, headache, and myalgia (muscle pain).

    Drugs: Calcium · Zinc · Cholesterol
    Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 protease
  2. Drug

    Bacillus calmette-guerin substrain connaught live antigen

    go.drugbank.com/drugs/DB10804
    ApprovedInvestigationalWithdrawn

    Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary

  3. Indication

    Upper Respiratory Tract Infection

    go.drugbank.com/conditions/DBCOND0035535
    Drugs: Acetaminophen · Amoxicillin · Bacampicillin · Cefoperazone · Cefpodoxime · Ceftibuten +8 more
    Synonyms: Acute upper respiratory infections of unspecified site
  4. Drug

    Teicoplanin

    go.drugbank.com/drugs/DB06149
    ApprovedInvestigationalWithdrawn

    All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety. … Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4).

    Products: TARGOCID INJECTION 200MG, TARGOCID 200mg POWDER FOR SOLUTION FOR INJECTION/INFUSION
  5. Drug

    Troleandomycin

    go.drugbank.com/drugs/DB13179
    Approved

    A macrolide antibiotic that is similar to erythromycin.

  6. Drug

    Almonertinib

    go.drugbank.com/drugs/DB16640
    ApprovedInvestigational

    [A231859, A231864, A231869] Unlike other third-generation EGFR TKIs, almonertinib is a pyrimidine-based drug that forms a covalent bond to the binding site of the EGFR tyrosine kinase domain.

  7. Drug

    Rilpivirine

    go.drugbank.com/drugs/DB08864
    ApprovedInvestigational

    [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's

    Mixtures: COMPLERA FILM-COATED TABLET 200MG/25MG/300MG, Odefsey® (200mg Emtricitabine/25mg Rilpivirine/25mg Tenofovir alafenamide) film coated tablets
  8. Pathway

    Atorvastatin Action Pathway

    smpdb.ca/view/SMP0000131
    Drug action

    Statins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it. … Reported side effects of atorvastatin include constipation, flatulence, dyspepsia (indigestion), abdominal pain, headache, and myalgia (muscle pain).

    Drugs: Calcium · Zinc · Cholesterol
    Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 protease
  9. Drug

    Vitamin D

    go.drugbank.com/drugs/DB11094
    ApprovedInvestigationalNutraceuticalVet approved

    Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to huma...

    Mixtures: Croq-vit Pour Enfants, Supravite Pour Enfants
  10. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barri...

    Mixtures: ISICOM 100MG/25MG, ISICOM 100MG/25MG