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Omega-3 fatty acids
go.drugbank.com/drugs/DB11133ApprovedInvestigationalNutraceuticalfish oil that originally come from microalgae that is further consumed by phytoplankton, a source of diet for fish). … Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S.
Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA, K-OMEGASQUA (Softgel)Multifunctional protein CAD
go.drugbank.com/bio_entities/BE0002227TargetEnzymeHumansMultifunctional protein that encodes the first 3 enzymatic activities of the de novo pyrimidine pathway: carbamoylphosphate synthetase (CPSase; EC 6.3.5.5), aspartate transcarbamylase (ATCase; EC 2.1.3.2) and dihydroorotase (DHOase; EC 3...
Polypeptides: Multifunctional protein CADLymphoblastic Lymphoma
go.drugbank.com/conditions/DBCOND0032667Synonyms: Non-Hodgkin lymphoma, no ICD-O subtype, Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)Olanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigational[A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] … Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.
Synonyms: 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepineInternational brands: CO OlanzapineInhibitor of nuclear factor kappa-B kinase subunit epsilon
go.drugbank.com/bio_entities/BE0009450TargetHumansThus, several scaffolding molecules including IPS1/MAVS, TANK, AZI2/NAP1 or TBKBP1/SINTBAD can be recruited to the IKBKE-containing-complexes (PubMed:17568778). … Serine/threonine kinase that plays an essential role in regulating inflammatory responses to viral infection, through the activation of the type I IFN, NF-kappa-B and STAT signaling (PubMed:16840782, PubMed
Synonyms: IKK-i, I-kappa-B kinase epsilonDantron
go.drugbank.com/drugs/DB04816ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Mixtures: Regulex D CapInternational brands: Scatron DPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
go.drugbank.com/bio_entities/BE0000571TargetEnzymeHumansTogether with PDHB forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex (PubMed:17474719, PubMed:19081061). The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby li...
Synonyms: PDHE1-A type ILoteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedAs a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. … Most prescription LE products, however, tend to be indicated for the treatment of post-operative inflammation and pain following ocular surgery [FDA Label].
Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, LOTEMICIN®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEctonucleotide pyrophosphatase/phosphodiesterase family member 3
go.drugbank.com/bio_entities/BE0011403TargetHumansAlso hydrolyzes extracellular 2',3'-cGAMP (cyclic GMP-AMP), a second messenger that activates TMEM173/STING and triggers type-I interferon production, and is therefore involved in the regulation of innate … Can hydrolyze extracellular dinucleoside polyphosphates, including the vasoactive adenosine polyphosphates as well (PubMed:12846830).
Synonyms: Alkaline phosphodiesterase I, Phosphodiesterase I betaDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).
Mixtures: NEUMOLEX® NF, BUCOXOL ® GRIP MAX CAPSULAS DURAS CON CONTENIDO LIQUIDOCategories: Histamine H1 Antagonists, Non-Sedating, P-glycoprotein inhibitors