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Displaying results 961 - 970 of 10000 in total
  1. Target

    Nuclear receptor subfamily 4 group A member 3

    go.drugbank.com/bio_entities/BE0008998
    TargetHumans

    Transcriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. … Binds to NBRE motif in CCND1 promoter, resulting in the activation of the promoter and CCND1 transcription (By similarity).

    Synonyms: Translocated in extraskeletal chondrosarcoma
  2. Target

    Serine/threonine-protein kinase Nek4

    go.drugbank.com/bio_entities/BE0009498
    TargetHumans

    Required for normal cell cycle arrest in response to double-stranded DNA damage

    Synonyms: Never in mitosis A-related kinase 4
  3. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    in the epithelium[A32373]. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism

    Synonyms: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamideMixtures: Daily all in one ample, Daily all in one ample
  4. Indication

    Nasal Polyps

    go.drugbank.com/conditions/DBCOND0004147
    Drugs: Budesonide
    Synonyms: Polyp in anterior nares
  5. Indication

    Chronic Phase Chronic Myeloid Leukemia

    go.drugbank.com/conditions/DBCOND0057382
    Drugs: Asciminib · Bosutinib · Dasatinib · Daunorubicin · Nilotinib · Ponatinib
    Synonyms: CML in Chronic Phase, Chronic Myeloid Leukemia in Chronic Phase
  6. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]

    Products: Vibramycin Inj
  7. Target

    Stromal cell-derived factor 1

    go.drugbank.com/bio_entities/BE0001150
    TargetHumans

    Induces down-regulation and internalization of ACKR3 expressed in various cells. … Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 in a CXCR4-independent manner (PubMed:29301984).

    Synonyms: Intercrine reduced in hepatomas
  8. Target

    Nuclear factor NF-kappa-B p100 subunit

    go.drugbank.com/bio_entities/BE0002387
    TargetHumans

    NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which

    Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
  9. Drug

    Tyrosine

    go.drugbank.com/drugs/DB00135
    ApprovedInvestigationalNutraceutical

    Tyrosine is a non-essential amino acid. In animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.

    Mixtures: AMINOPLASMAL 15% IN 500ML GLASS BOTTLE, 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
  10. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.

    Mixtures: OLIVIA QUIDO FIRM and FADE I, OLIVIA QUIDO FIRM and FADE IICategories: Corticosteroids, Weak (Group I)