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Displaying results 961 - 970 of 6949 in total
  1. Target

    5-hydroxytryptamine receptor 1D

    go.drugbank.com/bio_entities/BE0000659
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1565658, PubMed:1652050, PubMed:33762731). … Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances (PubMed:10452531, PubMed:1565658, PubMed:1652050, PubMed:33762731

    Polypeptides: 5-hydroxytryptamine receptor 1DSynonyms: Serotonin receptor 1D, Serotonin 1D alpha receptor
  2. Target

    Retinoic acid receptor alpha

    go.drugbank.com/bio_entities/BE0000663
    TargetHumans

    Receptor for retinoic acid (PubMed:16417524, PubMed:19850744, PubMed:20215566, PubMed:21152046, PubMed:37478846).

    Polypeptides: Retinoic acid receptor alphaSynonyms: Nuclear receptor subfamily 1 group B member 1
  3. Target

    Thyroid hormone receptor alpha

    go.drugbank.com/bio_entities/BE0000687
    TargetHumans

    Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

    Polypeptides: Thyroid hormone receptor alphaSynonyms: Nuclear receptor subfamily 1 group A member 1
  4. Target

    Cysteinyl leukotriene receptor 1

    go.drugbank.com/bio_entities/BE0000705
    TargetHumans

    Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma.

    Polypeptides: Cysteinyl leukotriene receptor 1Synonyms: LTD4 receptor, G protein-coupled receptor HG55
  5. Target

    Epidermal growth factor receptor

    go.drugbank.com/bio_entities/BE0000767
    TargetEnzymeHumans

    Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling (PubMed:11602604). … Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:10805725, PubMed:12297050,

    Polypeptides: Epidermal growth factor receptorSynonyms: Receptor tyrosine-protein kinase erbB-1
  6. Target

    Metabotropic glutamate receptor 1

    go.drugbank.com/bio_entities/BE0000824
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 1Function: adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
  7. Target

    Metabotropic glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000833
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 4Function: adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
  8. Target

    Metabotropic glutamate receptor 8

    go.drugbank.com/bio_entities/BE0000835
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 8Function: G protein-coupled receptor activity
  9. Target

    Hepatocyte growth factor receptor

    go.drugbank.com/bio_entities/BE0000915
    TargetHumans

    Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.

    Polypeptides: Hepatocyte growth factor receptorSynonyms: HGF receptor, SF receptor
  10. Target

    Endothelial protein C receptor

    go.drugbank.com/bio_entities/BE0001161
    TargetHumans

    Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation

    Polypeptides: Endothelial protein C receptorSynonyms: APC receptor, Activated protein C receptor