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Displaying results 981 - 990 of 10000 in total
  1. Target

    Vasoactive intestinal polypeptide receptor 1

    go.drugbank.com/bio_entities/BE0013137
    TargetHumans

    G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:35477937, PubMed:36385145, PubMed

    Polypeptides: Vasoactive intestinal polypeptide receptor 1Synonyms: VPAC1 receptor, PACAP type II receptor
  2. Target

    GDNF family receptor alpha-1

    go.drugbank.com/bio_entities/BE0013583
    TargetHumans

    GDNF-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977)

    Polypeptides: GDNF family receptor alpha-1Synonyms: GDNF receptor alpha-1, TGF-beta-related neurotrophic factor receptor 1
  3. Target

    Corticotropin-releasing hormone receptor 2

    go.drugbank.com/bio_entities/BE0014244
    TargetHumans

    G protein-coupled receptor for CRH, UCN, UCN2 and UCN3 stress hormones, which plays a central role in whole body adaptation to stress (PubMed:11329063, PubMed:11416224, PubMed:20966082, PubMed:22689579

    Polypeptides: Corticotropin-releasing hormone receptor 2Synonyms: Corticotropin-releasing factor receptor 2
  4. Target

    Interleukin-10 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0014391
    TargetHumans

    Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.

    Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1
  5. Target

    G protein-coupled receptor 68

    go.drugbank.com/bio_entities/BE0014724
    TargetHumans

    The receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (PubMed:12955148, PubMed:39753132). … Proton-sensing G protein-coupled receptor activated by extracellular pH, which is required to monitor pH changes and generate adaptive reactions (PubMed:12955148, PubMed:29677517, PubMed:32865988, PubMed

    Polypeptides: G protein-coupled receptor 68Synonyms: G protein-coupled receptor 12A, Ovarian cancer G protein-coupled receptor 1
  6. Target

    G protein-coupled receptor 84

    go.drugbank.com/bio_entities/BE0020007
    TargetHumans

    G protein-coupled receptor that responds endogenously to dietary fatty acids or nutrient, specifically medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. … In immune cells, functions as a pro-inflammatory receptor via 6-OAU and promotes the expression of pro-inflammatory mediators such as TNFalpha, IL-6 and IL-12B as well as stimulating chemotactic responses

    Polypeptides: G protein-coupled receptor 84Synonyms: Inflammation-related G protein-coupled receptor EX33
  7. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    [A234349] It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability. … [A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects.

    Mixtures: FITODERM TC, GENTAMICINA E BETAMETASONE IDIProducts: Gentamicin(e), INYECCION DE SULFATO DE GENTAMICINA ISOTONICA 1.6 MG/ ML
  8. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    to produce or synthesize the insulin needed to manage circulating blood sugar levels. … Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal muscle.

    Mixtures: Novolin Ge 30/70, Novolin Ge 30/70Products: Novolin Ge Nph, Novolin Ge Toronto
  9. Drug

    Niacin

    go.drugbank.com/drugs/DB00627
    ApprovedInvestigationalNutraceutical

    Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

    Mixtures: Folika-T, TL-Fluorivite
  10. Drug

    Zinc sulfate

    go.drugbank.com/drugs/DB09322
    ApprovedInvestigational

    Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". … It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

    Mixtures: Micro+ Te Pediatric, M T E 4 Concentrate InjProducts: SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE.