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Alemtuzumab
go.drugbank.com/drugs/DB00087
ApprovedInvestigational
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant reg...
Refractory Idiopathic thrombocytopenic purpura
go.drugbank.com/conditions/DBCOND0020771Steroid Refractory Acute Graft Versus Host Disease (SR aGVHD)
go.drugbank.com/conditions/DBCOND0162211Secondary Progressive Multiple Sclerosis (SPMS)
go.drugbank.com/conditions/DBCOND0049960Ofatumumab
go.drugbank.com/drugs/DB06650ApprovedInvestigationalOfatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by reco...
Kidney Transplant Rejection
go.drugbank.com/conditions/DBCOND0066662Drugs: Alemtuzumab · Antilymphocyte immunoglobulin (horse) · Azathioprine · Belatacept · Cyclosporine · Everolimus +2 more