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  1. Pathway

    Disulfiram Action Pathway

    smpdb.ca/view/SMP0000429
    Drug action

    Disulfiram is a drug used in the treatment of cocaine addiction and chronic alcoholism. With regards to cocaine addiction, cocaine inhibits dopamine reuptake by blocking dopamine transporter 1 (DAT1). This increases dopamine concentratio...

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Adenosine phosphate · Tyrosine +27 more
  2. Pathway

    Ethanol GABA Agonist Action Pathway

    smpdb.ca/view/SMP0125151
    Drug action

    Ethanol, commonly seen in the form of various alcohols as well as hand sanitizer, is a drug that is injected intrathecally. Ethanol's effects are mainly seen in the brain where it binds to many receptors. The main effects are seen by the...

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Ethanol · Calcium · Magnesium cation +3 more
  3. Pathway

    Cocaine metabolism

    smpdb.ca/view/SMP0125265
    Metabolic

    Cocaine is a local anaesthetic used for diagnostic procedures or surgery on or through the nasal cavity. It is administered as a spray in the nose where it enters the blood vessels of the nose and travels through the body. When taken ill...

    Drugs: Ethanol · Cocaine · Mesoheme
  4. Pathway

    Ethanol Degradation

    smpdb.ca/view/SMP0000449
    Metabolic

    Ethanol metabolism in humans occurs mainly in the liver, though degradation has also been shown in gastric, pancreatic, and lung tissue. Ethanol degradation occurs via four pathways, three of which are oxidative pathways and are depicted...

    Drugs: Adenosine phosphate · NADH · ATP · Ethanol · Zinc · Mesoheme +2 more
  5. Pathway

    Disulfiram Aldehyde Dehydrogenase Inhibitor Action Pathway

    smpdb.ca/view/SMP0122693
    Drug action

    Disulfiram is a carbamate derivative used to treat chronic alcoholism. It irreversibly inhibits aldehyde dehydrogenase in the mitochondrial matrix which converts acetaldehyde to acetic acid causing an accumulation of acetaldehyde. The hi...

    Drugs: Adenosine phosphate · NADH · ATP · Disulfiram · Ethanol · Zinc +3 more
  6. Pathway

    Ethanol Glycine Agonist Action Pathway

    smpdb.ca/view/SMP0126452
    Drug action

    Ethanol, commonly seen in the form of various alcohols as well as hand sanitizer, is a drug that is injected intrathecally. Ethanol's effects are mainly seen in the brain where it binds to many receptors. The main effects are seen by the...

    Drugs: Glycine · Ethanol · Calcium
  7. Pathway

    Ethanol NMDA Antagonist Action Pathway

    smpdb.ca/view/SMP0126453
    Drug action

    Ethanol, commonly seen in the form of various alcohols as well as hand sanitizer, is a drug that is injected intrathecally. Ethanol's effects are mainly seen in the brain where it binds to many receptors. The main effects are seen by the...

    Drugs: L-Glutamine · Glutamic acid · Ethanol · Calcium