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Displaying results 1 - 10 of 225 in total
  1. Target

    O-methyltransferase

    go.drugbank.com/bio_entities/BE0003784
    TargetEnzymeSynechocystis sp. (strain PCC 6803 / Kazusa)

    Polypeptides: O-methyltransferase
  2. Target

    Carnitine O-acetyltransferase

    go.drugbank.com/bio_entities/BE0000496
    TargetEnzymeHumans

    Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates (PubMed:23485643) … Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio.

    Polypeptides: Carnitine O-acetyltransferase
  3. Target

    Choline O-acetyltransferase

    go.drugbank.com/bio_entities/BE0000519
    EnzymeTargetHumans

    Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses

    Polypeptides: Choline O-acetyltransferaseFunction: choline O-acetyltransferase activity
  4. Target

    Galactoside O-acetyltransferase

    go.drugbank.com/bio_entities/BE0001404
    TargetEscherichia coli (strain K12)

    Catalyzes the CoA-dependent transfer of an acetyl group to the 6-O-methyl position of a range of galactosides, glucosides, and lactosides (PubMed:14009486, PubMed:4630409, PubMed:7592843).

    Polypeptides: Galactoside O-acetyltransferaseSynonyms: Acetyl-CoA:galactoside 6-O-acetyltransferase
  5. Target

    Catechol O-methyltransferase

    go.drugbank.com/bio_entities/BE0002089
    TargetEnzymeHumans

    Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. … Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol

    Polypeptides: Catechol O-methyltransferaseFunction: catechol O-methyltransferase activity
  6. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0002715
    TargetEscherichia coli (strain K12)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:10194342, PubMed:8335646). Does not show detectable N-acylamino acid racemase (NAAAR) activity with N-acetyl-S-methionine as subst...

    Polypeptides: o-succinylbenzoate synthaseSynonyms: o-succinylbenzoic acid synthase
  7. Target

    O-GlcNAcase NagJ

    go.drugbank.com/bio_entities/BE0003351
    TargetClostridium perfringens (strain 13 / Type A)

    Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O-glycosylated peptides from mammals. … Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).

    Polypeptides: O-GlcNAcase NagJFunction: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
  8. Target

    Acetylserotonin O-methyltransferase

    go.drugbank.com/bio_entities/BE0003553
    EnzymeHumans

    Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine)

    Polypeptides: Acetylserotonin O-methyltransferaseSynonyms: Hydroxyindole O-methyltransferase
  9. Target

    O-GlcNAcase BT_4395

    go.drugbank.com/bio_entities/BE0004258
    TargetBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

    Can hydrolyze the glycosidic link of O-GlcNAcylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).

    Polypeptides: O-GlcNAcase BT_4395Function: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
  10. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0004273
    TargetThermobifida fusca (strain YX)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444). Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substra...

    Polypeptides: o-succinylbenzoate synthaseSynonyms: o-succinylbenzoic acid synthase