Search

Displaying all 10 results
  1. Target

    Nicotinamide phosphoribosyltransferase

    go.drugbank.com/bio_entities/BE0002413
    TargetHumans

    Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathwa...

    Synonyms: Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1
  2. Target

    Mesothelin

    go.drugbank.com/bio_entities/BE0003459
    TargetHumans

    Membrane-anchored forms may play a role in cellular adhesion

    Synonyms: Pre-pro-megakaryocyte-potentiating factor
  3. Target

    Porphobilinogen deaminase

    go.drugbank.com/bio_entities/BE0001758
    TargetEscherichia coli (strain K12)

    Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

    Synonyms: Pre-uroporphyrinogen synthase
  4. Target

    Splicing factor 3B subunit 5

    go.drugbank.com/bio_entities/BE0018936
    TargetHumans

    The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA … Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077, PubMed:33509932)

    Synonyms: Pre-mRNA-splicing factor SF3b 10 kDa subunit
  5. Target

    Serine/arginine-rich splicing factor 4

    go.drugbank.com/bio_entities/BE0009120
    TargetHumans

    Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10

    Synonyms: Pre-mRNA-splicing factor SRP75
  6. Target

    Splicing factor 3B subunit 1

    go.drugbank.com/bio_entities/BE0009359
    TargetHumans

    The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA … Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077, PubMed:33509932).

    Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit
  7. Target

    Serine/threonine-protein kinase PRP4 homolog

    go.drugbank.com/bio_entities/BE0009527
    TargetHumans

    Connects chromatin mediated regulation of transcription and pre-mRNA splicing (PubMed:12077342). … Associates with U5 snRNP and NCOR1 deacetylase complexes which may allow a coordination of pre-mRNA splicing with chromatin remodeling events involved in transcriptional regulation (PubMed:12077342).

    Synonyms: PRP4 pre-mRNA-processing factor 4 homolog
  8. Target

    Splicing factor 3B subunit 3

    go.drugbank.com/bio_entities/BE0009020
    TargetHumans

    The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA … Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077, PubMed:33509932)

    Synonyms: Pre-mRNA-splicing factor SF3b 130 kDa subunit
  9. Target

    Serine/arginine-rich splicing factor 1

    go.drugbank.com/bio_entities/BE0009139
    TargetHumans

    Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC.

    Synonyms: pre-mRNA-splicing factor SF2, P33 subunit
  10. Target

    Stromal cell-derived factor 1

    go.drugbank.com/bio_entities/BE0001150
    TargetHumans

    Stimulates the proliferation of bone marrow-derived B-cell progenitors in the presence of IL7 as well as growth of stromal cell-dependent pre-B-cells (By similarity)

    Synonyms: Pre-B cell growth-stimulating factor