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GABA-Transaminase Deficiency: beta-alanine
smpdb.ca/view/SMP0125596DiseaseSymptoms of this disorder include low muscle tone and psychomotor retardation, as well as potential epilepsy and excessive sleeping.
Quazepam Action Pathway
smpdb.ca/view/SMP0126138Drug actiona desirable target in the treatment of epilepsy. … The inhibitory potentials produced by GABA neurotransmission play an integral role in the suppression and control of epileptiform nerve firing such as that seen in epilepsy, which makes the GABA system
Remimazolam Action Pathway
smpdb.ca/view/SMP0126145Drug actiona desirable target in the treatment of epilepsy. … The inhibitory potentials produced by GABA neurotransmission play an integral role in the suppression and control of epileptiform nerve firing such as that seen in epilepsy, which makes the GABA system
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 moreFlunarizine Calcium Channel Artery Dilation Action Pathway
smpdb.ca/view/SMP0126303Drug actionIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Levetiracetam Action Pathway (New)
smpdb.ca/view/SMP0126676Drug actionLevetiracetam is an oral anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy.
Methylphenobarbital Action Pathway
smpdb.ca/view/SMP0126819Drug actionIt serves to alleviate anxiety, tension, and apprehension, also functioning as an anticonvulsant for epilepsy treatment. … Mephobarbital, a barbiturate, undergoes metabolism into phenobarbital and has been employed for similar purposes, particularly in managing epilepsy; however, there exists no evidence supporting its superiority
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Methylphenobarbital · Calcium · Magnesium cation +3 moreNMDA
smpdb.ca/view/SMP0127051PhysiologicalTherefore, NMDARs are important therapeutic targets for many CNS disorders including stroke, hypoxia, ischemia, head trauma, Huntington’s, Parkinson’s, and Alzheimer’s diseases, epilepsy, neuropathic pain
AICA-Ribosiduria
smpdb.ca/view/SMP0000168DiseaseSymptoms include mental retardation, epilepsy, dysmorphic features, and congenital blindness.
Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +24 morePyridoxine Dependency with Seizures
smpdb.ca/view/SMP0000571DiseaseThe condition pyridoxine dependent-epilepsy is a condition that sees seizures beginning in infancy. In some cases, the seizures begin before birth.
Drugs: Pyridoxal phosphate · Lysine · Glutamic acid · NADH · Oxogluric acid · Flavin adenine dinucleotide +1 moreCarbamazepine Metabolism Pathway
smpdb.ca/view/SMP0000634Drug metabolismCarbamazepine is a drug used in the treatment of epilepsy, bipolar disorder, trigeminal neuralgia, and other psychiatric disorders. … Oxcarbazepine, an anticonvulsant used primarily in the treatment of epilepsy, is converted to 10,11-dihydroxycarbamazepine via 10-hydroxycarbazepine.