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Displaying results 1 - 10 of 14 in total
  1. Pathway

    Etizolam Action Pathway

    smpdb.ca/view/SMP0125057
    Drug action

    Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. … Etizolam allosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-gated chloride channel in different sites of the central nervous system (CNS).

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 more
  2. Pathway

    Acylcarnitine (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine

    smpdb.ca/view/SMP0123554
    Metabolic

    (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2Z)-2-(propan-2-yl)but-2-enedioyl-CoA reacts with L-carnitine to form (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Pathway

    Non-Ketotic Hyperglycinemia

    smpdb.ca/view/SMP0000223
    Disease

    Non Ketotic Hyperglycinemeia (Glycine encephalopathy; Glycine cleavage system deficiency; NKH) is caused by mutations in several genes in the mitochondrial glycine cleavage system.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  4. Pathway

    Non-Ketotic Hyperglycinemia

    smpdb.ca/view/SMP0125580
    Disease

    Non Ketotic Hyperglycinemeia (Glycine encephalopathy; Glycine cleavage system deficiency; NKH) is caused by mutations in several genes in the mitochondrial glycine cleavage system.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  5. Pathway

    Hyperglycinemia, Non-Ketotic

    smpdb.ca/view/SMP0000485
    Disease

    Currently there is no cure for Nonketotic hyperglycinemia therefore treatment involves managing symptoms. Frequency for Nonketotic hyperglycinemia has not been documented worldwide. … Other symptoms start presenting in the first few days of life and include lethargy, hypotonia, and myoclonic jerks, and progressing to apnea.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  6. Pathway

    Acylcarnitine non-4-enoylcarnitine

    smpdb.ca/view/SMP0123415
    Metabolic

    non-4-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-4-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-4-enoyl-CoA and L-carnitine. non-4

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  7. Pathway

    Acylcarnitine non-7-enoylcarnitine

    smpdb.ca/view/SMP0123418
    Metabolic

    non-7-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-7-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-7-enoyl-CoA and L-carnitine. non-7

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  8. Pathway

    Acylcarnitine non-6-enoylcarnitine

    smpdb.ca/view/SMP0123419
    Metabolic

    non-6-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-6-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-6-enoyl-CoA and L-carnitine. non-6

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  9. Pathway

    Acylcarnitine non-4-enedioylcarnitine

    smpdb.ca/view/SMP0123426
    Metabolic

    non-4-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, non-4-enedioyl-CoA reacts with L-carnitine to form non-4-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Pathway

    Acylcarnitine non-5-enoylcarnitine

    smpdb.ca/view/SMP0123416
    Metabolic

    non-5-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-5-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-5-enoyl-CoA and L-carnitine. non-5

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more