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  1. Pathway

    Etizolam Action Pathway

    smpdb.ca/view/SMP0125057
    Drug action

    Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. … Etizolam allosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-gated chloride channel in different sites of the central nervous system (CNS).

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 more
  2. Pathway

    Aldosterone from Steroidogenesis

    smpdb.ca/view/SMP0121126
    Physiological

    Angiotensin II from the circulation binds to receptors on the zona glomerulosa cell membrane, activating the G protein and triggering a signaling cascade. … From there, cholesterol undergoes a series of reactions in both the mitochondrion and the smooth endoplasmic reticulum (steroidogenesis) where it finally becomes aldosterone.

    Drugs: NADH · Progesterone · Mesoheme · Cholesterol · Corticosterone
  3. Pathway

    Acylcarnitine (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine

    smpdb.ca/view/SMP0123554
    Metabolic

    -2-enedioylcarnitine from forming and thereby preventing it from being transported into the mitochondria. … The general role of acylcarnitines is to transport acyl-groups, organic acids and fatty acids, from the cytoplasm into the mitochondria so that they can be broken down to produce energy.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more