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Plasmepsin I

During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an essential step which...

Signal peptidase I

Colicin I receptor

Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB.

DNA polymerase I

It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template.

Apolipoprotein A-I

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPA...

DNA polymerase I

In addition to polymerase activity, the recombinant enzyme has strand displacement and 5'-3' exonuclease activity, but lacks proofreading 3'-5' exonuclease activity.

Complement factor I

The presence of these cofactors on healthy cells allows degradation of deposited C3b by CFI in order to prevent undesired complement activation, while in apoptotic cells or microbes, the absence of such

DNA polymerase I, thermostable

In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). Unlikely to have 3'-5' exonuclease activity due to absence of a 3'-5' exonuclease domain (Probable).

Type I iodothyronine deiodinase

Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:32718224, PubMed:18821722). Catalyzes the deiodination of L-thyroxine (T4) ...

Keratin, type I cytoskeletal 16

Structural component of intermediate filaments in epithelial keratinocytes. Forms heteropolymers with type II keratins KRT6A and KRT6B, assembling into keratin intermediate filament networks that contribute to cytoskeletal resilience of ...