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Displaying results 1 - 10 of 430 in total
  1. Target

    Copper transport protein ATOX1

    go.drugbank.com/bio_entities/BE0002833
    TargetCarrierHumans

    Multifunctional copper-sensing protein that operates both as a cytosolic copper chaperone and as a copper-dependent transcription factor. … In the cytosol, transfers copper to the copper-transporting ATPase ATP7A at the trans-Golgi network, which is required for activation of secretory copper enzymes including lysyl oxidase (LOX) and SOD3.

    Polypeptides: Copper transport protein ATOX1Synonyms: Metal transport protein ATX1
  2. Target

    Serine hydrolase BPHL

    go.drugbank.com/bio_entities/BE0004370
    TargetHumans

    Catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir, converting them into their active forms (acyclovir and ganciclovir) (PubMed

    Synonyms: Valacyclovir hydrolase
  3. Target

    Sex hormone-binding globulin

    go.drugbank.com/bio_entities/BE0000685
    CarrierTargetHumans

    Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid.

    Polypeptides: Sex hormone-binding globulinSynonyms: Sex steroid-binding protein
  4. Target

    Cystine/glutamate transporter

    go.drugbank.com/bio_entities/BE0000030
    TargetTransporterHumans

    In vitro can also transport L-aspartate (PubMed:11417227). … Also inhibits ferroptosis by acting as an atypical proton transporter that mediates a slow proton efflux from lysosomes via cystine and glutamate flux (PubMed:40280132).

    Polypeptides: Cystine/glutamate transporterSynonyms: Amino acid transport system xc-
  5. Target

    Monocarboxylate transporter 6

    go.drugbank.com/bio_entities/BE0000386
    TargetTransporterHumans

    Proton-linked monocarboxylate transporter. … Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies

    Polypeptides: Monocarboxylate transporter 6Synonyms: Monocarboxylate transporter 5
  6. Target

    Monocarboxylate transporter 4

    go.drugbank.com/bio_entities/BE0000449
    TargetTransporterHumans

    Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate (PubMed:11101640, PubMed:23935841, PubMed:31719150).

    Polypeptides: Monocarboxylate transporter 4
  7. Target

    Ammonium transporter AmtB

    go.drugbank.com/bio_entities/BE0001338
    TargetEscherichia coli (strain K12)

    Transport is electrogenic (PubMed:30211659, PubMed:32662768). … In vitro can also transport the larger analogs methylamine and methylammonium (PubMed:11847102, PubMed:12023896, PubMed:14668330, PubMed:15876187, PubMed:17998534, PubMed:18362341).

    Polypeptides: Ammonium transporter AmtBSynonyms: Ammonia transporter
  8. Target

    Thiamine transporter 1

    go.drugbank.com/bio_entities/BE0003530
    TransporterHumans

    Mediates H(+)-dependent pyridoxine transport (PubMed:33008889, PubMed:35512554, PubMed:35724964) … High-affinity transporter for the intake of thiamine (PubMed:10391222, PubMed:10542220, PubMed:21836059, PubMed:33008889, PubMed:35512554, PubMed:35724964).

    Polypeptides: Thiamine transporter 1Function: folic acid transmembrane transporter activity
  9. Target

    Monocarboxylate transporter 10

    go.drugbank.com/bio_entities/BE0003654
    TransporterHumans

    Sodium- and proton-independent thyroid hormones and aromatic acids transporter (PubMed:11827462, PubMed:18337592, PubMed:28754537). … Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa) (PubMed:11827462, PubMed:28754537

    Polypeptides: Monocarboxylate transporter 10Synonyms: Aromatic amino acid transporter 1, T-type amino acid transporter 1
  10. Target

    Nucleoside transporter 2

    go.drugbank.com/bio_entities/BE0009258
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Nucleoside transporter 2Function: nucleoside transmembrane transporter activity