Sex hormone-binding globulin

BE0000685ProteinHumansSHBG

Functions as an androgen transport protein, but may also be involved in receptor mediated processes. It is acted on by 70 drugs in DrugBank.

Gene name
SHBG
UniProtKB entry
P04278Swiss-Prot
Cellular location
Secreted
Residues / weight
402 residues · 43,779 Da
Also known as
ABP · SBP · Sex steroid-binding protein · SHBG · TeBG

Resolves to

Protein
UniProtP04278UniProt nameSHBG_HUMAN
Gene
HGNCHGNC:10839NCBI Gene6462GenBank296673GeneCardsSHBG
Pharmacology
KEGGhsa:6462
Structure
PDB1D2SPDB1F5FPDB1KDK
Drugs

What you can answer from here — as of September 07, 2019

70DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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205+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sex hormone-binding globulin, how selective are they, and which programs against it are still in active trials?

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